5-Chloro-2',6'-difluoro-[1,1'-biphenyl]-3-ol CAS 1262002-75-4
| CAS No. | 1262002-75-4 |
| Molecular Formula | C12H7ClF2O |
| Molecular Weight | 240.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 5-Chloro-2',6'-difluoro-[1,1'-biphenyl]-3-ol is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 240.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
5-Chloro-2',6'-difluoro-[1,1'-biphenyl]-3-ol (CAS 1262002-75-4), molecular formula C12H7ClF2O and molecular weight 240.63 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Chloro-2',6'-difluoro-[1,1'-biphenyl]-3-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H7ClF2O |
| Molecular Weight | 240.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 5-Chloro-3',4'-difluoro-[1,1'-biphenyl]-3-ol (CAS 1261902-17-3)
- 3-Chloro-5-(3,5-difluorophenyl)phenol (CAS 1261919-72-5)
- 3-Chloro-5-(2,3-difluorophenyl)phenol (CAS 1261960-95-5)
- 5-Chloro-2',5'-difluoro-[1,1'-biphenyl]-3-ol (CAS 1261990-27-5)
- 3-Chloro-5-(2,4-difluorophenyl)phenol (CAS 1262002-54-9)
- 2-Chloro-2,2-difluoro-1-(naphthalen-1-yl)ethan-1-one (CAS 1352209-82-5)
- 3-Chloro-5-(trifluoromethyl)pyridine-2-carbothioamide (CAS 175277-46-0)
- Methyl 5-chloro-3,6-dimethylisoxazolo[5,4-b]pyridine-4-carboxylate (CAS 1011398-40-5)
Recommended Standards
- 2-((1,1,1-Trifluoropropan-2-yl)oxy)ethane-1-sulfonyl chloride (CAS 1536004-18-8)
- 3-(Trifluoromethylthio)benzoyl chloride (CAS 51748-28-8)
- 4-(Trifluoromethylthio)benzoyl Chloride (CAS 330-14-3)
- 3-(2,2,2-Trifluoroethoxy)propane-1-sulfonyl chloride (CAS 1250624-89-5)
- Methyl 3-[(4-Fluorophenyl)(hydroxy)methyl]isoxazole-4-carboxylate (CAS 2006277-87-6)
- 2-Bromo-3-nitropyridin-4(1H)-one (CAS 99035-23-1)
- 6-(4-BRomophenyl)-2-(4-fluorophenyl)imidazo[2,1-b][1,3]thiazole (CAS 881040-03-5)
- Pyridin-2-yl(4-(trifluoromethyl)phenyl)methanol (CAS 122377-18-8)
- 2,4-Dimethyl-2,4-pentanediol (CAS 24892-49-7)
- 6-Bromo-2-chloro-3H-imidazo[4,5-b]pyridine (CAS 438190-89-7)
- 2-(4-(Difluoromethyl)-2-hydroxy-5-iodopyridin-3-yl)acetonitrile (CAS 1807113-28-5)
- N-(4-chlorophenyl)-2,4-dimethoxybenzenesulfinamide (CAS 338982-02-8)
- 5-Hydroxyimino-3-methyl-1,2-dihydro-3-benzazepin-4-one (CAS 253324-90-2)
- Tetrapeptide-3 (CAS 827306-97-8)
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