5-Chloro-2',5'-difluoro-[1,1'-biphenyl]-3-ol CAS 1261990-27-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1261990-27-5
Molecular FormulaC12H7ClF2O
Molecular Weight240.63 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Chloro-2',5'-difluoro-[1,1'-biphenyl]-3-ol CAS 1261990-27-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 240.63 g/mol gives 5-Chloro-2',5'-difluoro-[1,1'-biphenyl]-3-ol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 5-Chloro-2',5'-difluoro-[1,1'-biphenyl]-3-ol (CAS 1261990-27-5), a certified reference material (molecular formula C12H7ClF2O, MW 240.63 g/mol) for analytical method development and quality control.

5-Chloro-2',5'-difluoro-[1,1'-biphenyl]-3-ol (C12H7ClF2O) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H7ClF2O
Molecular Weight240.63 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF/Cl-containing

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