Trazodone Hydrochloride EP Impurity J CAS 1263358-12-8
| CAS No. | 1263358-12-8 |
| Molecular Formula | C19H21Cl2N5O |
| Molecular Weight | 406.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Trazodone Hydrochloride EP Impurity J meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Trazodone Hydrochloride EP Impurity J (CAS 1263358-12-8) is a certified pharmaceutical impurity reference standard with the molecular formula C19H21Cl2N5O and a molecular weight of 406.31 g/mol.
Based on its molecular formula C19H21Cl2N5O, Trazodone Hydrochloride EP Impurity J contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 406.31 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C19H21Cl2N5O |
| Molecular Weight | 406.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Trazodone Standards
- Trazodone impurity 54 (CAS 55290-67-0)
- Trazodone impurity 53 (CAS 1346603-99-3)
- Trazodone Impurity 108 (CAS CATO-C4X-1772108)
- Trazodone EP Impurity E (CAS 1346599-35-6)
- Trazodone EP Impurity D (CAS 1263358-13-9)
- Trazodone Impurity 92 (CAS CATO-C4X-177292)
- Trazodone impurity 62 (CAS CATO-C4X-177262)
- Trazodone Impurity 110 (CAS CATO-C4X-1772110)
Recommended Standards
- Pioglitazone impurity 50 (CAS CATO-C4X-138350)
- Furazolidone Impurity 7 (CAS CATO-C4X-29017)
- 4-Chloro-N-(3-chloro-4-(2-(piperidin-1-yl)acetamido)phenyl)benzamide (CAS 332376-81-5)
- (2S,4S)-1-Boc-2-[4-(4-bromophenyl)-2-imidazolyl]-4-methylpyrrolidine (CAS 1250939-45-7)
- Dimetindene Maleate EP Impurity E Hydrochloride (CAS 5143-99-7)
- Spironolactone Impurity 16 (CAS CATO-C4X-134516)
- Levonorgestrel Impurity 43 (CAS 2762739-33-1)
- Methyl 4-hydroxyadamantan-1-carboxylate (CAS 81968-76-5)
- 2-Ethylhydrazine-1-carbothioamide (CAS 21149-56-4)
- 2-Cyano-N-(hexan-2-yl)acetamide (CAS 1365969-68-1)
- 3-Methylimidazo[4,5-f]quinoline (CAS 14692-41-2)
- 2-(2-Oxocyclohexyl)-6-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)pyridazin-3(2H)-one (CAS 171050-40-1)
- N-(3-Fluorophenyl)pentanamide (CAS 443121-94-6)
- Semaglutide Impurity 140 (CAS CATO-C4X-2226140)
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