Trazodone EP Impurity D CAS 1263358-13-9
| CAS No. | 1263358-13-9 |
| Molecular Formula | C19H22BrN5O |
| Molecular Weight | 416.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Trazodone EP Impurity D (CAS 1263358-13-9, C19H22BrN5O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C19H22BrN5O, Trazodone EP Impurity D contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 416.31 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H22BrN5O |
| Molecular Weight | 416.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 5 |
Related Trazodone Standards
- Trazodone Impurity 92 (CAS CATO-C4X-177292)
- Trazodone Hydrochloride EP Impurity J (CAS 1263358-12-8)
- Trazodone impurity 54 (CAS 55290-67-0)
- Trazodone impurity 53 (CAS 1346603-99-3)
- Trazodone Impurity 106 (CAS CATO-C4X-1772106)
- Trazodone Impurity 108 (CAS CATO-C4X-1772108)
- Trazodone EP Impurity E (CAS 1346599-35-6)
- Trazodone Impurity 31 (CAS CATO-C4X-177231)
Recommended Standards
- beta-Cypermethrin(Mixture of isomers) (CAS 1224510-29-5)
- di-tert-Butyl 3-bromo-6,6-dimethylpyrrolo[3,4-c]pyrazole-2,5(4H,6H)-dicarboxylate (CAS 1330766-42-1)
- zeta-Cypermethrin (CAS 1315501-18-8)
- 5-Bromo-N-(4-(2-methoxyphenoxy)but-2-yn-1-yl)thiophene-2-sulfonamide (CAS 1428350-30-4)
- Cyclandelate Impurity 3 (CAS CATO-C4X-22853)
- Fosaprepitant Impurity 21 (CAS 265121-01-5)
- Linaclotide Impurity 28 (CAS CATO-C4X-210628)
- 1-Methyl-2-[({2-methylpyrazolo[1,5-a]pyrazin-4-yl}oxy)methyl]pyrrolidine (CAS 2198436-15-4)
- 5-(1-(Ethylsulfonyl)piperidin-3-yl)-4-(4-fluorobenzyl)-4H-1,2,4-triazole-3-thiol (CAS 932807-07-3)
- 4-[[2-Chloro-5-(Trifluoromethyl)Phenyl]Hydrazinylidene]-N-(2-Methylphenyl)-3-Oxo-Naphthalene-2-Carboxamide (CAS 17618-85-8)
- 2-(Benzo[d]isoxazol-3-yl)-1-(4-((prop-2-yn-1-yloxy)methyl)piperidin-1-yl)ethan-1-one (CAS 1251692-09-7)
- 5-Bromo-2,3-dihydro-1-benzofuran-7-sulfonyl chloride (CAS 690632-00-9)
- (S)-4-(tert-butyl)-2-(2-(diphenylphosphanyl)-5-(trifluoromethyl)phenyl)-4,5-dihydrooxazole (CAS 944836-21-9)
- Semaglutide Main Chain P29 (CAS 1169630-82-3)
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