Trazodone impurity 54 CAS 55290-67-0
| CAS No. | 55290-67-0 |
| Molecular Formula | C19H24ClN5O3 |
| Molecular Weight | 405.88 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Trazodone impurity 54 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Trazodone impurity 54 (CAS 55290-67-0) is a certified pharmaceutical impurity reference standard with the molecular formula C19H24ClN5O3 and a molecular weight of 405.88 g/mol.
Based on its molecular formula C19H24ClN5O3, Trazodone impurity 54 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 405.88 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Trazodone impurity 54 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H24ClN5O3 |
| Molecular Weight | 405.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Trazodone Standards
- Trazodone Hydrochloride EP Impurity J (CAS 1263358-12-8)
- Trazodone impurity 53 (CAS 1346603-99-3)
- Trazodone Impurity 108 (CAS CATO-C4X-1772108)
- Trazodone EP Impurity E (CAS 1346599-35-6)
- Trazodone EP Impurity D (CAS 1263358-13-9)
- Trazodone Impurity 92 (CAS CATO-C4X-177292)
- Trazodone impurity 62 (CAS CATO-C4X-177262)
- Trazodone Impurity 110 (CAS CATO-C4X-1772110)
Recommended Standards
- 4-[4-(Benzyloxy)phenyl]-1-[(4-chlorophenyl)methyl]-3-methyl-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 860786-56-7)
- N-(2-(1H-indol-3-yl)ethyl)-2-(4-chloro-2-methylphenoxy)nicotinamide (CAS 946386-62-5)
- 1,2-Dibromo-1h,1h,2h-perfluorohexane (CAS 236736-19-9)
- N-(4-(Benzo[d]thiazol-2-yl)-2-fluorophenyl)-7-chloroquinolin-4-amine (CAS 920520-18-9)
- Rupatadine impurity 47 (CAS CATO-C4X-102747)
- Edoxaban Impurity 97 (Mixture of Diastereomers) (CAS CATO-C4X-106397)
- Rosuvastatin Impurity 24 (CAS 894787-93-0)
- 1-(3-Bromobenzyl)-2-methylbenzene (CAS 2484889-27-0)
- Dimethyl 2-(5-chloropyrimidin-4-yl)propanedioate (CAS 809276-87-7)
- 1,10-Bis-(dichloracetamido)-decan (CAS 6945-00-2)
- 4-(Dibenzo[b,d]furan-3-yl)butanoic acid (CAS 6948-74-9)
- 4-{[5-(4-chlorophenyl)-1,2-oxazol-3-yl]methyl}morpholine (CAS 343374-69-6)
- N-(2-amino-2-methylpropyl)-2-methylpropanamide (CAS 58027-59-1)
- D-[Ser]8-Liraglutide (CAS CATO-C4X-199238)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com