6,8-Difluoro-1-methyl-2-oxo-1,2-dihydroquinoline-4-carboxylic acid CAS 1268148-41-9
| CAS No. | 1268148-41-9 |
| Molecular Formula | C11H7F2NO3 |
| Molecular Weight | 239.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6,8-Difluoro-1-methyl-2-oxo-1,2-dihydroquinoline-4-carboxylic acid (C11H7F2NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
6,8-Difluoro-1-methyl-2-oxo-1,2-dihydroquinoline-4-carboxylic acid (CAS 1268148-41-9), molecular formula C11H7F2NO3 and molecular weight 239.17 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6,8-Difluoro-1-methyl-2-oxo-1,2-dihydroquinoline-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H7F2NO3 |
| Molecular Weight | 239.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- Methyl 6,8-difluoro-4-oxo-1,4-dihydroquinoline-2-carboxylate (CAS 1065074-53-4)
- 7,8-Difluoro-2-methoxyquinoline-4-carboxylic acid (CAS 1125702-51-3)
- 5,8-Difluoro-1-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 1267907-33-4)
- 6,7-Difluoro-1-methyl-2-oxo-1,2-dihydroquinoline-4-carboxylic acid (CAS 1269529-65-8)
- Methyl 6,7-difluoro-4-oxo-1,4-dihydroquinoline-2-carboxylate (CAS 1282252-23-6)
- 6,8-Difluoro-4-methoxyquinoline-2-carboxylic acid (CAS 1338651-82-3)
- 6,7-Difluoro-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 144298-26-0)
- 6,8-Difluoro-1-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 191730-01-5)
Recommended Standards
- 5-[(2,5-Difluorophenyl)methyl]-1,2-oxazole-3-carboxylic Acid (CAS 1258503-80-8)
- (R)-2-amino-2-(3-fluoro-4-(trifluoromethoxy)phenyl)ethan-1-ol (CAS 1213874-86-2)
- 2-[2-(3,4-difluorophenyl)-1,3-oxazol-4-yl]acetic acid (CAS 1311316-26-3)
- (S)-2-amino-2-(3-fluoro-4-(trifluoromethoxy)phenyl)ethan-1-ol (CAS 1213402-51-7)
- 5-Chloro-3-methyl-3,4-dihydro-2H-[1,3'-biquinolin]-2-one (CAS 918646-16-9)
- 6-Methoxy-3-(3-methoxybenzoyl)quinolin-4(1H)-one (CAS 892291-35-9)
- 4-((4-Aminobenzylidene)amino)aniline (CAS 55133-44-3)
- Alarmine (CAS 105-10-2)
- Metopimazine Metabolite (CAS 18182-00-8)
- 2-(Pyrrolidin-1-yl)thiazole-5-carbaldehyde (CAS 900015-48-7)
- 2-(2,6-difluorophenyl)acetamide (CAS 1006608-67-8)
- (R)-tert-Butyl 1-(3-fluorobenzyl)pyrrolidin-3-ylcarbamate (CAS 876162-15-1)
- (5-Nitroisothiazol-3-yl)methanol (CAS 2271348-91-3)
- Endo-38a-Pro-Exenatide trifluoroacetate salt (CAS 1678416-95-9)
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