Methyl 6,7-difluoro-4-oxo-1,4-dihydroquinoline-2-carboxylate CAS 1282252-23-6
| CAS No. | 1282252-23-6 |
| Molecular Formula | C11H7F2NO3 |
| Molecular Weight | 239.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Methyl 6,7-difluoro-4-oxo-1,4-dihydroquinoline-2-carboxylate (C11H7F2NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Methyl 6,7-difluoro-4-oxo-1,4-dihydroquinoline-2-carboxylate (CAS 1282252-23-6), a certified reference material (molecular formula C11H7F2NO3, MW 239.17 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 6,7-difluoro-4-oxo-1,4-dihydroquinoline-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H7F2NO3 |
| Molecular Weight | 239.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- Methyl 6,8-difluoro-4-oxo-1,4-dihydroquinoline-2-carboxylate (CAS 1065074-53-4)
- 7,8-Difluoro-2-methoxyquinoline-4-carboxylic acid (CAS 1125702-51-3)
- 5,8-Difluoro-1-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 1267907-33-4)
- 6,8-Difluoro-1-methyl-2-oxo-1,2-dihydroquinoline-4-carboxylic acid (CAS 1268148-41-9)
- 6,7-Difluoro-1-methyl-2-oxo-1,2-dihydroquinoline-4-carboxylic acid (CAS 1269529-65-8)
- 6,8-Difluoro-4-methoxyquinoline-2-carboxylic acid (CAS 1338651-82-3)
- 6,7-Difluoro-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 144298-26-0)
- 6,8-Difluoro-1-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 191730-01-5)
Recommended Standards
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