methyl (S)-(1-((4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2-yl)amino)propan-2-yl)carbamate CAS 1269440-60-9
| CAS No. | 1269440-60-9 |
| Molecular Formula | C15H21IN6O2 |
| Molecular Weight | 444.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies methyl (S)-(1-((4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2-yl)amino)propan-2-yl)carbamate (CAS 1269440-60-9), a certified reference material (molecular formula C15H21IN6O2, MW 444.27 g/mol) for analytical method development and quality control.
The molecular framework of methyl (S)-(1-((4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2-yl)amino)propan-2-yl)carbamate (C15H21IN6O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), methyl (S)-(1-((4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2-yl)amino)propan-2-yl)carbamate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H21IN6O2 |
| Molecular Weight | 444.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 6 |
Recommended Standards
- 4,4,5,5-tetramethyl-2-[10-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)anthracen-9-yl]-1,3,2-dioxaborolane 863992-56-7 AS-2438 (CAS 863992-56-7)
- tert-Butyl-(R)-3-(4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate, 97% (CAS 1276110-38-3)
- 2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-N-(4-chlorophenyl)pyridine-3-carboxamide (CAS 338412-91-2)
- (E)-4-((3,4-dichlorobenzyl)oxy)-N'-(3-nitrobenzylidene)benzohydrazide (CAS 303987-29-3)
- 1-Chloro-2,3-dimethyl-4-nitrobenzene (CAS 50536-78-2)
- 3-(Benzyloxy)-2-(bromomethyl)-2-fluoro-1-propanol (CAS 865451-83-8)
- [S-(R*,S*)]-5-[1-Hydroxy-2-[(1-methyl-3-phenylpropyl)(phenylmethyl)amino]ethyl]-2-(phenylmethoxy)benzamide (CAS 81580-37-2)
- (2-Chloro-4-fluorophenyl)(4-(piperidin-1-ylmethyl)phenyl)methanone (CAS 898775-44-5)
- 4-Trifluoromethyl-N-methyl-benzenepropanamine (CAS 459872-43-6)
- Fluralaner Impurity 63 (CAS 3027861-23-7)
- (1R,3S,4S)-tert-butyl 3-((2-amino-4-bromophenyl)carbamoyl)-2-azabicyclo[2.2.1]heptane-2-carboxylate (CAS 1256387-73-1)
- 1H-Pyrazole-1-carboximidamide (CAS 4023-00-1)
- 3-Chloro-6-(2-fluoro-4-methylphenyl)pyridazine (CAS 669770-60-9)
- Semaglutide Impurity 7 (CAS CATO-C4X-22267)
Why CATO?
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