2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-N-(4-chlorophenyl)pyridine-3-carboxamide CAS 338412-91-2
| CAS No. | 338412-91-2 |
| Molecular Formula | C18H10Cl2F3N3OS |
| Molecular Weight | 444.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-N-(4-chlorophenyl)pyridine-3-carboxamide is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-N-(4-chlorophenyl)pyridine-3-carboxamide (CAS 338412-91-2) is a high-purity analytical reference standard with the molecular formula C18H10Cl2F3N3OS and a molecular weight of 444.26 g/mol.
Owing to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-N-(4-chlorophenyl)pyridine-3-carboxamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 444.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-N-(4-chlorophenyl)pyridine-3-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H10Cl2F3N3OS |
| Molecular Weight | 444.26 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related chloro Standards
- 2-Chloro-N-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)thio)phenyl)nicotinamide (CAS 1024069-88-2)
- 2-({5-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]pyrimidin-2-yl}sulfanyl)-1-(4-chlorophenyl)ethan-1-one (CAS 344263-13-4)
- 3-((2-Chloro-6-fluorobenzyl)thio)-5-(4-chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazole (CAS 477331-50-3)
- 4-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-iodo-6-nitrophenol (CAS 1400872-24-3)
- 3-Chloro-6'-(2,4-dichlorophenoxy)-5-(trifluoromethyl)-[2,3'-bipyridine]-5'-carbonitrile (CAS 339011-79-9)
- N-(2-Chloro-4-methylphenyl)-2-[4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]acetamide (CAS 1775346-92-3)
- N-(2-Chloro-4-methylphenyl)-2-[4-(5-ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]acetamide (CAS 1775402-61-3)
- N-(3-Chloro-4-methylphenyl)-2-[4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]acetamide (CAS 1775403-67-2)
Recommended Standards
- 4,4,5,5-tetramethyl-2-[10-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)anthracen-9-yl]-1,3,2-dioxaborolane 863992-56-7 AS-2438 (CAS 863992-56-7)
- stat3 inhibitor DISCONTINUED. Please see S687205. (CAS 1041438-68-9)
- methyl (S)-(1-((4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2-yl)amino)propan-2-yl)carbamate (CAS 1269440-60-9)
- tert-Butyl-(R)-3-(4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate, 97% (CAS 1276110-38-3)
- 5,5,5-Trifluoro-1-(pyridin-3-yl)pentan-2-one (CAS 1341290-61-6)
- 2-Amino-N,N-diethyl-2-methylpropanamide hydrochloride (CAS 65853-90-9)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-5-fluoro-4-(methylthio)pyrimidine (CAS 1823182-63-3)
- 3-Amino-N-(5-chloro-2-methylphenyl)benzamide (CAS 897595-54-9)
- 3-hydroxy-4-methylpyridine-2-carboxylic acid hydrochloride (CAS 2060030-04-6)
- 7-Chloro-3-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one (CAS 4699-82-5)
- Methyl 2-cyano-2-(2,3-difluoro-6-nitrophenyl)acetate (CAS 2055119-07-6)
- N-Acetyl Mesalamine-d3 Impurity 1 (CAS 1309935-89-4)
- 3-Bromo-6,7-dihydro-5H-cyclopenta[b]pyridine-7-carboxylic acid (CAS 1972580-93-0)
- Semaglutide impurity 78 (CAS CATO-C4X-222678)
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