Lifitegrast Impurity N77 CAS 1270132-45-0
| CAS No. | 1270132-45-0 |
| Molecular Formula | C10H13NO4S |
| Molecular Weight | 243.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Lifitegrast Impurity N77 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Lifitegrast Impurity N77 (CAS 1270132-45-0), a pharmacopoeial impurity reference standard (molecular formula C10H13NO4S, MW 243.28 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C10H13NO4S, Lifitegrast Impurity N77 contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 243.28 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C10H13NO4S |
| Molecular Weight | 243.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Lifitegrast Standards
- Lifitegrast Impurity N99 (CAS 1195655-47-0)
- Lifitegrast Impurity 116 (CAS CATO-C4X-2409116)
- Lifitegrast Impurity 96 (CAS 1270093-99-6)
- Lifitegrast Impurity 161 (CAS CATO-C4X-2409161)
- Lifitegrast Impurity 27 (CAS 14046-52-7)
- Lifitegrast Impurity 167 (CAS CATO-C4X-2409167)
- Lifitegrast Impurity 110 (CAS 2091680-73-6)
- Lifitegrast Impurity 62 (CAS CATO-C4X-240962)
Recommended Standards
- 5-Cyclopropoxy-4-(methylamino)pyridine-3-sulfonamide (CAS 1243481-01-7)
- 2-Amino-1-(3-fluoro-2-methylphenyl)-4,5-dimethyl-1H-pyrrole-3-carbonitrile (CAS 1283855-09-3)
- 6-(Aminomethyl)-5-cyclopropoxypyridine-2-sulfonamide (CAS 1243470-56-5)
- Ethyl 5-(Ethylsulfonyl)pyridine-2-carboxylate (CAS 1314406-40-0)
- Ezetimibe Impurity 6 (CAS CATO-C4X-10986)
- Celecoxib Impurity 76 (CAS CATO-C4X-104376)
- Mianserin Impurity 97 (CAS 85141-92-0)
- 5-Methoxybenzofuran-2-carbaldehyde (CAS 23145-19-9)
- Z-Cys(pMeOBzl)-OH (CAS 3081-32-1)
- 4-oxa-7-azaspiro[2.5]octan-8-one (CAS 2227206-16-6)
- 2-Morpholinomethyl-4-trifluoromethylbenzophenone (CAS 898750-83-9)
- 3-(1-Aminoethyl)thietane 1,1-dioxide hydrochloride (CAS 2138083-60-8)
- Bis(4-methoxyphenyl)-4h-1,2,4-triazole-3-thiol (CAS 335396-34-4)
- Palmitoyl Tripeptide-8 TFA salt (CAS 936544-53-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com