Sertraline Impurity 69 CAS CATO-C4X-134469
| CAS No. | CATO-C4X-134469 |
| Molecular Formula | C16H13ClO |
| Molecular Weight | 256.73 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Sertraline Impurity 69 (CAS CATO-C4X-134469, C16H13ClO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system, Sertraline Impurity 69 is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 256.73 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H13ClO |
| Molecular Weight | 256.73 g/mol |
| Purity | 95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Sertraline Standards
- Sertraline Impurity 29 (CAS 36159-73-6)
- Sertraline Impurity 71 (CAS CATO-C4X-134471)
- Sertraline Impurity 75 (CAS CATO-C4X-134475)
- Sertraline Impurity 46 (CAS CATO-C4X-134446)
- Sertraline - Impurity C (Freebase) (CAS 107538-91-0)
- Sertraline Impurity 45 (CAS CATO-C4X-134445)
- Sertraline EP Impurity D (1S, 4S-Isomer) (CAS 871838-58-3)
- Sertraline EP Impurity B (CAS 52758-03-9)
Recommended Standards
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- Mexiletine EP Impurity D(Enantiomer Mixture) (CAS 26583-71-1)
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- (6-Methylpyridin-2-yl)(4-(trifluoromethyl)phenyl)methanone (CAS 1187164-27-7)
- 2-Phenyl-1-(prop-2-yn-1-yl)-1h-imidazole hydrochloride (CAS 1269151-12-3)
- (1-(Thiomorpholinomethyl)cyclopropyl)methanol (CAS 2773311-19-4)
- N-(3-Phenylpropyl)-4-(thiophen-2-yl)tetrahydro-2H-pyran-4-carboxamide (CAS 877650-42-5)
- Liraglutide Impurity 30 (CAS CATO-C4X-199230)
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