2-[2,2-Difluoro-1-(MEM)ethenyl]-boronic acid pinacol ester CAS 1272412-65-3
| CAS No. | 1272412-65-3 |
| Molecular Formula | C12H21BF2O5 |
| Molecular Weight | 294.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-[2,2-Difluoro-1-(MEM)ethenyl]-boronic acid pinacol ester (CAS 1272412-65-3) is a high-purity analytical reference standard with the molecular formula C12H21BF2O5 and a molecular weight of 294.10 g/mol.
The molecular framework of 2-[2,2-Difluoro-1-(MEM)ethenyl]-boronic acid pinacol ester (C12H21BF2O5) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H21BF2O5 |
| Molecular Weight | 294.10 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.5 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
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- Semaglutide (CAS CATO-C4X-2226105)
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