Clarithromycin EP Impurity O CAS 127252-80-6
| CAS No. | 127252-80-6 |
| Molecular Formula | C39H72N2O13 |
| Molecular Weight | 776.99 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Clarithromycin EP Impurity O (CAS 127252-80-6) is a certified pharmaceutical impurity reference standard with the molecular formula C39H72N2O13 and a molecular weight of 776.99 g/mol.
Based on its molecular formula C39H72N2O13, Clarithromycin EP Impurity O contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 776.99 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C39H72N2O13 |
| Molecular Weight | 776.99 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 2 |
Related Clarithromycin Standards
- Clarithromycin EP Impurity G (CAS 127182-44-9)
- Clarithromycin Impurity 22 (CAS CATO-C4X-100222)
- Clarithromycin EP Impurity A (CAS 124412-58-4)
- Clarithromycin Impurity 19 (CAS CATO-C4X-100219)
- Clarithromycin Impurity 20 (CAS 118074-07-0)
- Clarithromycin 9-Oxime (CAS 103450-87-9)
- Clarithromycin EP Impurity C (CAS 127253-06-9)
- Clarithromycin EP Impurity L (CAS 127253-05-8)
Recommended Standards
- 108375-77-5 PC 766B Oxacyclohexadeca-3,5,11,13-tetraen-2-one, 16-((1S,2R,3S)-3-((2R,4R,5S,6R)-4-((2,6-dideoxy-beta-D-arabino-hexopyranosyl)oxy)tetrahydro-2-hydroxy-5-methyl-6-((1E,3E)-1,3-pentadienyl)-2H-pyran-2-yl)-2-hydroxy-1-methylbutyl)-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-, (3Z,5E,7R,8S,9S,11E,13E,15S,16R)- PC-766B (CAS 108375-77-5)
- 3,3,4,4,5,5,5-Heptafluoropentan-2-ol (CAS 85571-83-1)
- Azithromycin Impurity P (CAS CATO-C4X-100352)
- Semaglutide Impurity 176 (CAS CATO-C4X-2226176)
- Losartan Impurity 57 (CAS C4X-13305)
- Etizolam Impurity 14 (CAS 40054-57-7)
- Difelikefalin Impurity 97 (CAS CATO-C4X-304197)
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- 50675-18-8 2H-Pyran-4-carboxaldehyde, tetrahydro- Tetrahydro-2H-pyran-4-carboxaldehyde EC 700-032-1 (CAS 50675-18-8)
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Why CATO?
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