Ruxolitinib Impurity 186 CAS 941685-41-2
| CAS No. | 941685-41-2 |
| Molecular Formula | C23H32N6OSi |
| Molecular Weight | 436.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Ruxolitinib Impurity 186 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Ruxolitinib Impurity 186 (CAS 941685-41-2) is a certified pharmaceutical impurity reference standard with the molecular formula C23H32N6OSi and a molecular weight of 436.64 g/mol.
Structurally, Ruxolitinib Impurity 186 (C23H32N6OSi) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 436.64 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C23H32N6OSi |
| Molecular Weight | 436.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 6 |
Related Ruxolitinib Standards
- Ruxolitinib Impurity N4 (CAS 941685-40-1)
- Ruxolitinib Impurity N6 (CAS 941685-39-8)
- Ruxolitinib Impurity 24 (CAS CATO-C4X-205824)
- Ruxolitinib Impurity 25 (CAS CATO-C4X-205825)
- Ruxolitinib Impurity 56 (CAS CATO-C4X-205856)
- Ruxolitinib Impurity 173 (CAS 1236032-96-4)
- Ruxolitinib Impurity 55 (CAS CATO-C4X-205855)
- Ruxolitinib Impurity 8 Trifluoroacetate (CAS 2606144-44-7(free base))
Recommended Standards
- R-(+)-1,2-Bis(diphenylphosphino)propane 67884-32-6 (R)-(+)-BIS-(1,2-DIPHENYLPHOSPHINO)PROPANE;(R)-(+)-PROPHOS;(R)-(+)-PROPYLENEBIS(1,2-DIPHENYLPHOSPHINE);(R)-PROPHOS;R-(+)-1,2-BIS(DIPHENYLPHOSPHINO)PROPANE SC11384 (CAS 67884-32-6)
- Tri(1-adamantyl)phosphine (CAS 897665-73-5)
- 1,3-Bis(diphenylphosphino)propane 6737-42-4 1,3-BIS(DIPHENYLPHOSPHINE)PROPANE;1,3-BIS(DIPHENYLPHOSPHINO)PROPANE;1,3-BIS(DIPHENYPHOSPHINO)PROPANE;DPPP;PROPYLENEBIS(DIPHENYLPHOSPHINE);TRIMETHYLENEBIS(DIPHENYLPHOSPHINE);[3-(DIPHENYLPHOSPHANYL)PROPYL]DIPHENYLPHOSPHANE GC10105 (CAS 6737-42-4)
- 6-Deoxo-28-norcastasterone (CAS 169624-26-4)
- Rabeprazole Impurity 23 (CAS 86604-74-2)
- Lifitegrast impurity 91 (CAS CATO-C4X-240991)
- Azilsartan Impurity 160 (CAS CATO-C4X-1096160)
- Benzyl (2-(4-fluorophenyl)propan-2-yl)carbamate (CAS 1403483-60-2)
- Dihydro Isoferulic Acid 3-O-β-D-Glucuronide (CAS 1187945-72-7)
- 5-Chloro-6-(trifluoromethyl)nicotinic acid (CAS 749875-05-6)
- 4-Amino-5-chloro-2-(4-(trifluoromethyl)phenyl)pyridazin-3(2H)-one (CAS 923027-45-6)
- Lemborexant Impurity 50 (CAS CATO-C4X-304250)
- 4-Chloro-2-methoxy-5-methylpyridine (CAS 1227578-49-5)
- Liraglutide-d8 Tetratrifluoroacetate (CAS 204656-20-2 (non-labelled, free base))
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com