1-Benzyl-3-(2,2,2-trifluoro-ethyl)-piperazine-2,5-dione CAS 1279816-44-2
| CAS No. | 1279816-44-2 |
| Molecular Formula | C13H13F3N2O2 |
| Molecular Weight | 286.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Benzyl-3-(2,2,2-trifluoro-ethyl)-piperazine-2,5-dione.
1-Benzyl-3-(2,2,2-trifluoro-ethyl)-piperazine-2,5-dione (CAS 1279816-44-2), molecular formula C13H13F3N2O2 and molecular weight 286.25 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C13H13F3N2O2, 1-Benzyl-3-(2,2,2-trifluoro-ethyl)-piperazine-2,5-dione contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 286.25 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-Benzyl-3-(2,2,2-trifluoro-ethyl)-piperazine-2,5-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H13F3N2O2 |
| Molecular Weight | 286.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Benzyl Standards
- Methyl 3,3,3-trifluoro-2-(2-methylindol-3-yl)alaninate (CAS 1262415-77-9)
- (3E)-1,1,1-Trifluoro-4-[4-(pyrimidin-2-yl)piperazin-1-yl]but-3-en-2-one (CAS 691858-24-9)
- 1,1,1-Trifluoro-4-{[2-(1H-indol-3-yl)ethyl]amino}-2-butanol (CAS 692738-24-2)
- 4,4,4-TRifluoro-3-hydroxy-3-(trifluoromethyl)butyrophenone (CAS 731-00-0)
- 2,4,6-Trifluoro-3-iodobenzaldehyde (CAS 1160573-17-0)
- 2,2,2-Trifluoro-1-(3-nitro-5-(trifluoromethyl)phenyl)ethan-1-one (CAS 76911-72-3)
- 2,2,2-Trifluoro-N-(7-oxo-6,7-dihydro-5H-indeno[5,6-d][1,3]dioxol-5-yl)acetamide (CAS 138621-69-9)
- 4,4,4-Trifluoro-1-(3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)butane-1,3-dione (CAS 943994-23-8)
Recommended Standards
- Methyl 4-Oxo-1-(2,4,5-trifluorophenyl)cyclohexanecarboxylate (CAS 1385694-46-1)
- 4-(2-Hydroxyethyl)-3-methyl-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-5-ol (CAS 1239747-18-2)
- 4-Oxo-1-[4-(trifluoromethyl)phenyl]cyclohexanecarboxylic Acid (CAS 1385694-50-7)
- 4-(4-(2,2,2-Trifluoroacetyl)piperazin-1-yl)benzaldehyde (CAS 122648-76-4)
- 2-(Aminomethyl)-3-(difluoromethyl)-5-iodo-4-(trifluoromethyl)pyridine (CAS 1806987-43-8)
- ((1,1-Dioxidotetrahydrothiophen-3-yl)sulfonyl)glycine (CAS 926248-43-3)
- Methyl 3-amino-2,4-dihydroxybenzoate (CAS 956105-63-8)
- LSD-D3 (Lysergic acid diethylamide-D3) (CAS 136765-38-3)
- Avatrombopag Impurity 143 (CAS 2115508-48-8)
- Ethyl 4-{2-[(2,5-dihydro-1H-pyrrol-1-yl)methyl]benzoyl}benzoate (CAS 1017083-43-0)
- N1-benzyl-N1-methylbutane-1,4-diamine (CAS 221196-25-4)
- 5-(bromomethyl)-3-(2-methoxyphenyl)isoxazole (CAS 886364-40-5)
- 2-(5-(4-Chlorophenyl)-1H-pyrazol-3-yl)acetonitrile (CAS 134161-76-5)
- Semaglutide impurity 77 (CAS CATO-C4X-222677)
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