Escitalopram EP Impurity K CAS 128196-02-1
| CAS No. | 128196-02-1 |
| Molecular Formula | C20H21FN2O |
| Molecular Weight | 324.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Escitalopram EP Impurity K under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Escitalopram EP Impurity K (CAS 128196-02-1), a pharmacopoeial impurity reference standard (molecular formula C20H21FN2O, MW 324.39 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Escitalopram EP Impurity K (C20H21FN2O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C20H21FN2O |
| Molecular Weight | 324.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Escitalopram Standards
- EsCitalopram EP Impurity I (CAS 1370643-22-3)
- EsCitalopram Impurity 3 (CAS CATO-C4X-16343)
- ESCitalopram N-Oxide (CAS 917482-45-2)
- EsCitalopram EP Impurity H (CAS 63284-72-0)
- Escitalopram EP Impurity A(R-Isomer) (CAS CATO-C4X-110920)
- Escitalopram Impurity 2 (CAS 103146-25-4)
- Escitalopram EP Impurity M (CAS 1881237-26-8)
- Escitalopram EP Impurity F (CAS 2102609-59-4)
Recommended Standards
- 2-Oxo-6,9,12,15-tetraoxa-3-thiaoctadecan-18-oic acid (CAS 1263044-79-6)
- tert-Butyl 4-[(2-amino-4-fluorophenoxy)methyl]piperidine-1-carboxylate (CAS 1286264-60-5)
- (3,5-Difluorophenyl){[4-(morpholin-4-ylmethyl)-2-thienyl]methyl}amine (CAS 1242930-39-7)
- tert-Butyl 4-[(2-amino-6-fluorophenoxy)methyl]piperidine-1-carboxylate (CAS 1286264-77-4)
- Metformin EP Impurity D (CAS 108-78-1)
- Ziprasidone Impurity 36 (CAS CATO-C4X-124036)
- Ribociclib Impurity 22 (CAS CATO-C4X-310022)
- 2,5-Diamino-5,6-dihydropyrimidin-4(1H)-one (CAS 601507-12-4)
- 3-Bromo-6-methyl-2-nitroaniline (CAS 1780649-49-1)
- 4-(4-Methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline (CAS 109028-09-3)
- 2-{4-[(2-cyanopyridin-4-yl)oxy]phenyl}acetic acid (CAS 1423029-71-3)
- (4S)-4-amino-5-ethoxy-tetrahydrofuran-2-one (CAS 1315057-31-8)
- 1-(2-Bromo-4,5-dimethoxybenzyl)-6,7-dimethoxyisoquinoline (CAS 51449-10-6)
- Semaglutide impurity 196 (CAS CATO-C4X-2226196)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com