Minoxidil Impurity 21 CAS 128304-91-6
| CAS No. | 128304-91-6 |
| Molecular Formula | C6H10N4O2 |
| Molecular Weight | 170.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Minoxidil Impurity 21 (CAS 128304-91-6, C6H10N4O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Minoxidil Impurity 21 (C6H10N4O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Minoxidil Impurity 21 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H10N4O2 |
| Molecular Weight | 170.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 4 |
Related Minoxidil Standards
- Minoxidil Impurity 67 (CAS CATO-C4X-170067)
- Minoxidil Impurity 53 (CAS CATO-C4X-170053)
- Minoxidil Impurity 59 (CAS CATO-C4X-170059)
- Minoxidil Impurity 68 (CAS CATO-C4X-170068)
- Minoxidil Impurity 22 (CAS 56488-00-7)
- Minoxidil Impurity 66 (CAS CATO-C4X-170066)
- Minoxidil Impurity 70 (CAS CATO-C4X-170070)
- Minoxidil EP Impurity A (CAS 35139-67-4)
Recommended Standards
- Hydralazine Impurity 1 (CAS 234-80-0)
- Fluorouracil Impurity 27 (CAS 2566704-13-8)
- Riociguat Impurity N13 (CAS 6017-21-6)
- Fluorouracil Impurity 17 (CAS 5440-00-6)
- Pemafibrate Impurity 71 (CAS CATO-C4X-290371)
- Micafungin Impurity 12 (CAS CATO-C4X-169512)
- Cefpirome Impurity 21 (CAS CATO-C4X-120721)
- Argatroban Impurity 52 (CAS CATO-C4X-100752)
- 1,4-Dioxocane (CAS 6572-91-4)
- (t-Bu)PhCPhos (CAS 1660153-91-2)
- 4-bromo-2-fluoro-1-isocyanatobenzene (CAS 88112-75-8)
- Naltrexone impurity 65 (CAS 3075674-22-2)
- 6-(Cyclopent-3-en-1-yloxy)nicotinonitrile (CAS 1355334-42-7)
- Semaglutide impurity 331 (CAS CATO-C4X-2226231)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com