6-Fluoro-4-formylpicolinic acid CAS 1288995-49-2
| CAS No. | 1288995-49-2 |
| Molecular Formula | C7H4FNO3 |
| Molecular Weight | 169.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Fluoro-4-formylpicolinic acid.
6-Fluoro-4-formylpicolinic acid (CAS 1288995-49-2) is a high-purity analytical reference standard with the molecular formula C7H4FNO3 and a molecular weight of 169.11 g/mol.
6-Fluoro-4-formylpicolinic acid (C7H4FNO3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Fluoro-4-formylpicolinic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4FNO3 |
| Molecular Weight | 169.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 3-Fluoro-5-nitrobenzaldehyde (CAS 108159-96-2)
- 5-Fluoro-4-formylpicolinic acid (CAS 1289040-31-8)
- 4-Fluoro-6-formylpicolinic acid (CAS 1289073-88-6)
- 5-Fluoro-4-formylnicotinic acid (CAS 1289102-69-7)
- 5-Fluoro-6-formylpicolinic acid (CAS 1289114-12-0)
- 2-Fluoro-3-formylisonicotinic acid (CAS 1289160-52-6)
- 3-Fluoro-4-formylpicolinic acid (CAS 1289207-80-2)
- 5-Fluoro-6-formylnicotinic acid (CAS 1289211-53-5)
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