6-Chloro-1H-indazole-3-carboxylic Acid CAS 129295-31-4
| CAS No. | 129295-31-4 |
| Molecular Formula | C8H5ClN2O2 |
| Molecular Weight | 196.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-Chloro-1H-indazole-3-carboxylic Acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-Chloro-1H-indazole-3-carboxylic Acid (CAS 129295-31-4) is a high-purity analytical reference standard with the molecular formula C8H5ClN2O2 and a molecular weight of 196.59 g/mol.
6-Chloro-1H-indazole-3-carboxylic Acid (C8H5ClN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Chloro-1H-indazole-3-carboxylic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5ClN2O2 |
| Molecular Weight | 196.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 5-Chloro-2-methyl-4-nitrobenzonitrile (CAS 101495-54-9)
- 7-Chloro-2H-indazole-5-carboxylic acid (CAS 1031417-54-5)
- 3-Chloro-1H-indazole-5-carboxylic acid (CAS 1031417-73-8)
- 5-Chloro-1H-indazole-3-carboxylic acid (CAS 1077-95-8)
- 5-Chloro-2-methyl-3-nitro-benzonitrile (CAS 1082040-48-9)
- 2-(2-Chloro-3-nitrophenyl)acetonitrile (CAS 108772-95-8)
- 6-Chloro-1H-pyrrolo[2,3-b]pyridine-4-carboxylic acid (CAS 1167056-92-9)
- Methyl 3-chloro-2-cyano-pyridine-4-carboxylate (CAS 1168102-35-9)
Recommended Standards
- Methyl 2-chloro-4-cyanonicotinate (CAS 1289188-60-8)
- 7-Chloro-1H-indazole-3-carboxylic acid (CAS 129295-32-5)
- 4-Chloro-3-nitro-1h-indole (CAS 1279719-00-4)
- 7-Chloro-1H-benzo[d]imidazole-5-carboxylic acid (CAS 1301214-57-2)
- 1-(3-Bromo-4-methylphenyl)-2,5-dimethyl-1H-pyrrole (CAS 736973-12-9)
- (1,3-Dithian-2-yl)dimethylphosphine oxide (CAS 259529-90-3)
- 38870-89-2 T66S02B1S3 Methoxyacetyl chloride Acetyl chloride, methoxy- EINECS 254-169-2 NSC 82321 UNII-T66S02B1S3 (CAS 38870-89-2)
- 4-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid (CAS 1190313-91-7)
- Ethyl (Z)-3-(2-(2-cyanoacetyl)hydrazono)-4-methylpentanoate (CAS 477862-85-4)
- Empagliflozin Impurity 281 (CAS 1096342-71-0)
- 2-Chloro-3-(2-methoxyethylamino)naphthalene-1,4-dione (CAS 22272-22-6)
- 4,5,6,7-Tetrahydro-2H-pyrazolo[3,4-c]pyridine 2,2,2-trifluoroacetate (CAS 2088956-65-2)
- Vonoprazan Impurity 101 (CAS 1885094-62-1)
- Semaglutide Impurity 158 (x TFA Salt) (CAS CATO-C4X-2226158)
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