Letrozole Impurity 25 CAS 1250126-45-4
| CAS No. | 1250126-45-4 |
| Molecular Formula | C10H9N3O2 |
| Molecular Weight | 203.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Letrozole Impurity 25 (C10H9N3O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Letrozole Impurity 25 (CAS 1250126-45-4), a pharmacopoeial impurity reference standard (molecular formula C10H9N3O2, MW 203.20 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Letrozole Impurity 25 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H9N3O2 |
| Molecular Weight | 203.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 3 |
Related Letrozole Standards
- Letrozole Impurity 24 (CAS CATO-C4X-182924)
- Letrozole Impurity 33 (CAS 1461654-89-6)
- Letrozole Impurity 39 (CAS 28188-41-2)
- Letrozole Impurity 28 (CAS 46209-39-6)
- Letrozole Impurity 26 (CAS 870766-45-3)
- Letrozole impurity 01 (CAS 10466-37-2)
- Letrozole Impurity 14 (CAS 2451658-74-3)
- Letrozole Impurity 15 (CAS 74231-65-5)
Recommended Standards
- Suvorexant Impurity 39 (CAS 1293284-56-6)
- Alanyl Glutamine Impurity 45 (CAS CATO-C4X-197445)
- Suvorexant Impurity 18 (CAS 1785606-18-9)
- Nitroso L-Arginine (CAS 2492451-27-9)
- Tribenoside EP Impurity B (CAS 28713-39-5)
- Lefamulinum Impurity 23 (CAS CATO-C4X-304723)
- Revefenacin Impurity 67 (CAS CATO-C4X-203167)
- 3-(4-Fluorobenzylidene)-2-indolinone (CAS 3476-86-6)
- (2,5-Dimethylphenyl)(3-((4-methylpiperazin-1-yl)methyl)phenyl)methanone (CAS 898788-74-4)
- 1-(4-(Piperidin-4-yl)phenyl)ethan-1-ol hydrochloride (CAS 2140866-94-8)
- 3-(2-Phenoxyethoxy)azetidine (CAS 1220038-68-5)
- 3-(Chloromethyl)oxetane (CAS 87498-55-3)
- Ethyl 5-Bromopyrimidine-2-carboxylate (CAS 1197193-30-8)
- Peptide Impurity 26 (CAS 1350456-66-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com