Tofacitinib Impurity 63 CAS 1354469-76-3

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.1354469-76-3
Molecular FormulaC7H16N2
Molecular Weight128.22 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Tofacitinib Impurity 63 CAS 1354469-76-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 128.22 g/mol gives Tofacitinib Impurity 63 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

As a process- or degradation-related impurity, Tofacitinib Impurity 63 (CAS 1354469-76-3, C7H16N2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Owing to an organic framework, Tofacitinib Impurity 63 is typically white to off-white liquid. Its solid-state physicochemical attributes — including a molecular weight of 128.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Tofacitinib Impurity 63 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H16N2
Molecular Weight128.22 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)1.0
CAS Registry Year (est.)1991
Nitrogen Atoms2

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