Asenapine Impurity 7 CAS 129385-61-1
| CAS No. | 129385-61-1 |
| Molecular Formula | C17H10ClNO3 |
| Molecular Weight | 311.72 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Asenapine Impurity 7 (CAS 129385-61-1) is a certified pharmaceutical impurity reference standard with the molecular formula C17H10ClNO3 and a molecular weight of 311.72 g/mol.
Asenapine Impurity 7 (C17H10ClNO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H10ClNO3 |
| Molecular Weight | 311.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Asenapine Standards
- Asenapine Impurity 4 (CAS CATO-C4X-19474)
- Asenapine Impurity 5 (CAS CATO-C4X-19475)
- Asenapine N-Oxide (CAS 128949-51-9)
- Asenapine Impurity 3 (CAS CATO-C4X-19473)
- Asenapine Impurity 12 (CAS CATO-C4X-194712)
- Asenapine Impurity 1 (CAS 1180843-77-9)
- Asenapine-13C,d3 (CAS 1217729-73-1)
- Asenapine-d3 (CAS 1180843-72-4)
Recommended Standards
- Hydrochlorothiazide Impurity 18 (CAS 89813-56-9)
- (2E)-3-(3-Chlorophenyl)-2-{5-[(1H-1,2,4-triazol-1-yl)methyl]-1H-1,2,4-triazol-3-yl}prop-2-enenitrile (CAS 1164520-60-8)
- 501925-31-1 1-(5-Chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea Urea, N-(5-chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)- PNU-120596 NSC 216666 PNU 120596 (CAS 501925-31-1)
- 3-(4-Chlorophenyl)-2-[5-(1H-1,2,4-triazol-1-ylmethyl)-1H-1,2,4-triazol-3-yl]acrylonitrile (CAS 1164552-75-3)
- Indacaterol Impurity 41 (CAS 312759-81-2)
- Solifenacin Impurity 35 (CAS 7500-45-0)
- Elagolix Impurity 77 (CAS CATO-C4X-206877)
- Dapoxetine Impurity 21 (CAS 2941-20-0)
- 1-(3-((2-Chlorobenzyl)sulfonyl)-2-hydroxypropyl)pyrrolidin-2-one (CAS 400083-33-2)
- Methyl 2-Acetamido-4-chloro-5-methylbenzoate (CAS 755031-82-4)
- Ethyl 2-(5-(tert-butyl)-2-oxocyclohexyl)-2-oxoacetate (CAS 15839-52-8)
- 3-Chloro-N-hydroxy-2,2-dimethylpropanamide (CAS 81778-06-5)
- 6-fluoroquinolin-2-amine (CAS 791626-57-8)
- Insulin Lispro (CAS 133107-64-9)
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