Asenapine Impurity 4 CAS CATO-C4X-19474
| CAS No. | CATO-C4X-19474 |
| Molecular Formula | C17H14ClNO3 |
| Molecular Weight | 315.75 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Asenapine Impurity 4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Asenapine Impurity 4 (CAS CATO-C4X-19474, C17H14ClNO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Asenapine Impurity 4 (C17H14ClNO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 315.75 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C17H14ClNO3 |
| Molecular Weight | 315.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Asenapine Standards
- Asenapine Impurity 5 (CAS CATO-C4X-19475)
- Asenapine Impurity 7 (CAS 129385-61-1)
- Asenapine N-Oxide (CAS 128949-51-9)
- Asenapine Impurity 3 (CAS CATO-C4X-19473)
- Asenapine Impurity 12 (CAS CATO-C4X-194712)
- Asenapine Impurity 1 (CAS 1180843-77-9)
- Asenapine-13C,d3 (CAS 1217729-73-1)
- Asenapine-d3 (CAS 1180843-72-4)
Recommended Standards
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- Mesalamine Impurity 41 (CAS CATO-C4X-132441)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com