2-Nitro-4-(trifluoromethoxy)phenol CAS 129644-56-0
| CAS No. | 129644-56-0 |
| Molecular Formula | C7H4F3NO4 |
| Molecular Weight | 223.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Nitro-4-(trifluoromethoxy)phenol (C7H4F3NO4) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-Nitro-4-(trifluoromethoxy)phenol (CAS 129644-56-0), molecular formula C7H4F3NO4 and molecular weight 223.11 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Nitro-4-(trifluoromethoxy)phenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H4F3NO4 |
| Molecular Weight | 223.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Nitro Standards
- 2-Nitro-5-(trifluoromethoxy)phenol (CAS 1197236-32-0)
- 3-Nitro-4-(trifluoromethoxy)phenol (CAS 1214332-23-6)
- 4-Nitro-3-(trifluoromethoxy)phenol (CAS 1260654-90-7)
- 2-Nitro-6-(trifluoromethoxy)phenol (CAS 1261445-46-8)
- 4-Nitro-2-(trifluoromethoxy)phenol (CAS 1261753-93-8)
- 5-Nitro-2-(trifluoromethoxy)pyridin-4-amine (CAS 1361741-17-4)
- 1-Nitro-3-(1,2,2,2-tetrafluoroethyl)benzene (CAS 612844-88-9)
- 2-Nitro-4-(trifluoromethyl)benzene-1-thiol (CAS 14371-82-5)
Recommended Standards
- tert-Butyl 3-bromobutanoate (CAS 1268837-93-9)
- 2-Bromothiazole-4-carbothioamide (CAS 1333153-67-5)
- (2-bromo-3-methoxy-phenyl)hydrazine (CAS 1388065-78-8)
- Isopropyl 5-bromopentanoate (CAS 13931-38-9)
- [4'-(Methylsulfanyl)[1,1'-biphenyl]-3-yl]methanol (CAS 885965-25-3)
- 2-Amino-7-bromoisoquinolin-1(2H)-one (CAS 1935123-90-2)
- 6-Bromo-5-(difluoromethyl)-4-hydroxypicolinaldehyde (CAS 1806908-49-5)
- 1H-Indol-5-yl trifluoromethanesulfonate (CAS 128373-13-7)
- 2-Amino-6-(4-chlorophenyl)-4-phenylnicotinonitrile (CAS 75356-07-9)
- Propynenitrile DISCONTINUED (CAS 1070-71-9)
- 2-(Difluoromethoxy)-6-fluorocinnamic acid (CAS 1262012-57-6)
- 2-(3-Fluoro-4-isobutoxyphenyl)ethan-1-ol (CAS 1443327-77-2)
- Tetrahydroxydiboron (CAS 13675-18-8)
- Antiarrhythmic peptide (cattle atrium) (CAS 81771-37-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com