Ceftazidime Impurity 13 CAS 1301254-50-1
| CAS No. | 1301254-50-1 |
| Molecular Formula | C17H17N5O7S2 |
| Molecular Weight | 467.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Ceftazidime Impurity 13 (CAS 1301254-50-1, C17H17N5O7S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Ceftazidime Impurity 13 (C17H17N5O7S2) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 467.48 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H17N5O7S2 |
| Molecular Weight | 467.48 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 2 |
Related Ceftazidime Standards
- Ceftazidime Impurity 40 (CAS CATO-C4X-121240)
- Ceftazidime Impurity C68 (CAS 179258-52-7)
- Ceftazidime Impurity 73 (CAS CATO-C4X-121273)
- Ceftazidime Impurity 20 (CAS CATO-C4X-121220)
- Ceftazidime impurity 123 (CAS CATO-C4X-1212123)
- Ceftazidime Impurity 23 (CAS 158183-05-2)
- Ceftazidime Impurity 51 (CAS CATO-C4X-121251)
- Ceftazidime Impurity C07 (CAS 752152-44-6)
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