Sorafenib Impurity 10 CAS 2004659-85-0
| CAS No. | 2004659-85-0 |
| Molecular Formula | C13H12N2O2 |
| Molecular Weight | 228.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Sorafenib Impurity 10 (CAS 2004659-85-0, C13H12N2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Sorafenib Impurity 10 (C13H12N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Sorafenib Impurity 10 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H12N2O2 |
| Molecular Weight | 228.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 2 |
Related Sorafenib Standards
- Sorafenib Impurity 59 (CAS 284462-80-2)
- Sorafenib Impurity 21 (CAS CATO-C4X-112421)
- Sorafenib Impurity 30 (CAS 1012058-77-3)
- Sorafenib Impurity 45 (CAS 46843-47-4)
- Sorafenib Impurity 57 (CAS 656-96-2)
- Sorafenib Impurity 32 (CAS 50528-86-4)
- Sorafenib Impurity 12 (CAS 343247-69-8)
- Sorafenib Impurity 15 (CAS CATO-C4X-112415)
Recommended Standards
- Benidipine Impurity 46 (CAS 40034-60-4)
- Potassium Clavulanate impurity 22 (CAS 148601-26-7)
- Ibrutinib Impurity 81 (CAS 143667-36-1)
- Nafamostat impurity 126 (CAS CATO-C4X-1332126)
- Abemaciclib Impurity 31 4HCl (CAS CATO-C4X-293731)
- Terbutaline impurity 120 (CAS CATO-C4X-1183120)
- Manidipine impurity 3 (CAS CATO-C4X-27533)
- (2Z)-2-(4-Chlorobenzenesulfonyl)-3-[4-(dimethylamino)phenyl]prop-2-enenitrile (CAS 804515-70-6)
- Norlevo Mepromazine (CAS 37819-98-0)
- Methyl 2-amino-4-bromothiophene-3-carboxylate hydrochloride (CAS 1956383-43-9)
- Cyclohexylamine Hydroiodide (CAS 45492-87-3)
- 2-(6-Methylpyridin-2-yl)ethanamine (CAS 19363-94-1)
- (4S,5S)-4,5-bis(trifluoromethyl)-1,3-dioxolan-2-one (CAS 127213-78-9)
- Peptide YY (human) trifluoroacetate salt (CAS 118997-30-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com