5,5-Difluoropiperidin-3-one hydrochloride CAS 1303973-33-2
| CAS No. | 1303973-33-2 |
| Molecular Formula | C5H7F2NO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5,5-Difluoropiperidin-3-one hydrochloride is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5,5-Difluoropiperidin-3-one hydrochloride (CAS 1303973-33-2), molecular formula C5H7F2NOHCl and molecular weight 171.57 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C5H7F2NOHCl, 5,5-Difluoropiperidin-3-one hydrochloride contains an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic functional-group stretching vibrations in infrared spectroscopy. The molecular weight of 171.57 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5,5-Difluoropiperidin-3-one hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H7F2NO HCl |
| Molecular Weight | 171.57 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Difluoropiperidin Standards
- 1-Benzyl-3,3-difluoropiperidin-4-amine (CAS 1039741-55-3)
- 4,4-Difluoropiperidin-3-ol hydrochloride (CAS 1186688-54-9)
- 4,4-Difluoropiperidin-3-ol (CAS 1187087-19-9)
- 3-(4,4-Difluoropiperidin-1-yl)propanoic acid (CAS 1204295-05-5)
- 3,3-Difluoropiperidin-2-one (CAS 1206540-41-1)
- 1-Boc-3,3-difluoropiperidin-4-ol (CAS 1209780-71-1)
- 2-(4,4-Difluoropiperidin-1-yl)-2-phenylacetonitrile (CAS 1226998-22-6)
- 2-(4,4-Difluoropiperidin-1-yl)-2-phenylethanamine (CAS 1227040-43-8)
Recommended Standards
- (R)-tert-Butyl 4-(2-(4-(3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-yl)-2-oxoethyl)piperidine-1-carboxylate (CAS 193276-76-5)
- (E)-1-(4-methyl-2-phenylthiazol-5-yl)ethan-1-one O-cyclopropanecarbonyl oxime (CAS 860649-87-2)
- 2-((5-Ethyl-4-(naphthalen-1-yl)-4H-1,2,4-triazol-3-yl)thio)acetic acid (CAS 886498-37-9)
- 5-Oxa-2,7-diazaspiro[3.5]nonan-6-one (CAS 2137567-26-9)
- 2-(Tert-butyl) 5-methyl isoindoline-2,5-dicarboxylate (CAS 368441-44-5)
- Belinostat Amide (CAS 1485081-57-9)
- 1-((3,5-Dimethyl-1H-pyrazol-1-yl)methyl)-5-methyl-1H-pyrazole-3-carboxamide (CAS 1263214-27-2)
- 6-ethyl-3H,4H-thieno[2,3-d]pyrimidin-4-one (CAS 18593-51-6)
- 1-(3,4-Dimethylphenyl)cyclopentane-1-carboxylic acid (CAS 854414-87-2)
- Semaglutide impurity 77 (CAS CATO-C4X-222677)
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