Dorzolamide Hydrochloride CAS 130693-82-2
| CAS No. | 130693-82-2 |
| Molecular Formula | C10H16N2O4S3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Dorzolamide Hydrochloride (CAS 130693-82-2), a certified reference material (molecular formula C10H16N2O4S3HCl, MW 360.89 g/mol) for analytical method development and quality control.
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, Dorzolamide Hydrochloride is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 360.89 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H16N2O4S3 HCl |
| Molecular Weight | 360.89 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 3 |
Related Dorzolamide Standards
- Dorzolamide Impurity 8 (CAS 120279-26-7)
- Dorzolamide EP Impurity A HCl (CAS 120279-36-9)
- Dorzolamide EP Impurity B HCl (CAS 120279-37-0)
- Dorzolamide EP Impurity A (CAS 120279-95-0)
- Dorzolamide (CAS 120279-96-1)
- Rac-Dorzolamide (CAS 120280-13-9)
- Dorzolamide EP Impurity A HCl (CAS 122028-36-8)
- Dorzolamide-d5 (CAS 1227097-70-2)
Recommended Standards
- 2,3-DIOXOINDOLINE-5-CARBOXYLIC ACID (CAS 25128-32-9)
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- 2-(4-Methoxyphenoxy)acetamide (CAS 30893-64-2)
- 6-Fluoro-2-methylquinoline-5-carboxylic acid (CAS 86053-13-6)
- 2-(Chloromethyl)-1-fluoro-4-methoxybenzene (CAS 1076197-70-0)
- 2-Bromo-4,6-difluorobenzenesulfonamide (CAS 951624-79-6)
- 4,4'-Bicyclohexanol (mixture of isomers) (CAS 20601-38-1)
- 4-(4-(Methylthio)phenyl)-2H-pyrido[2,3-e][1,2,4]thiadiazin-3(4H)-one 1,1-dioxide (CAS 1707562-52-4)
- 4-[3,4-Dihydro-1(2H)-quinolinyl]-3-methylaniline (CAS 1094746-54-9)
- Cholecystokinin Octapeptide free acid (desulfated) (H-2075.0001) (CAS 103974-46-5)
Why CATO?
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