Dorzolamide EP Impurity A HCl CAS 120279-36-9
| CAS No. | 120279-36-9 |
| Molecular Formula | C10H16N2O4S3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Dorzolamide EP Impurity A HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Dorzolamide EP Impurity A HCl (CAS 120279-36-9), a pharmacopoeial impurity reference standard (molecular formula C10H16N2O4S3HCl, MW 360.89 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, Dorzolamide EP Impurity A HCl is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 360.89 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C10H16N2O4S3 HCl |
| Molecular Weight | 360.89 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 3 |
Related Dorzolamide Standards
- Dorzolamide Impurity 8 (CAS 120279-26-7)
- Dorzolamide EP Impurity B HCl (CAS 120279-37-0)
- Dorzolamide EP Impurity A (CAS 120279-95-0)
- Dorzolamide (CAS 120279-96-1)
- Rac-Dorzolamide (CAS 120280-13-9)
- Dorzolamide EP Impurity A HCl (CAS 122028-36-8)
- Dorzolamide-d5 (CAS 1227097-70-2)
- Dorzolamide Hydrochloride (CAS 130693-82-2)
Recommended Standards
- Pivmecillinam Impurity 15 (CAS CATO-C4X-232315)
- Lasmiditan Impurity 32 (CAS 3355-39-3)
- Nafamostat Impurity 50 (CAS CATO-C4X-133250)
- 7-Bromo-5-methylbenzo[e][1,2,4]triazin-3-amine (CAS 867330-26-5)
- Violaxanthin (CAS 126-29-4)
- N'-Benzylidene-2-((4,6-dimethylpyrimidin-2-yl)thio)acetohydrazide (CAS 60458-57-3)
- (S)-Benzyl 3-(oxetan-3-ylamino)piperidine-1-carboxylate (CAS 1349700-00-0)
- 3-Chloro-5-methoxy-4-[(3-nitrobenzyl)oxy]benzaldehyde (CAS 428502-97-0)
- Benzo[d]thiazole-6-thiol (CAS 854085-71-5)
- Peptide Impurity 04 (CAS 2913424-91-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com