5-Bromo-2-chloro-3-(trifluoromethyl)-phenylboronic acid CAS 1310403-90-7
| CAS No. | 1310403-90-7 |
| Molecular Formula | C7H4BBrClF3O2 |
| Molecular Weight | 303.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Bromo-2-chloro-3-(trifluoromethyl)-phenylboronic acid.
5-Bromo-2-chloro-3-(trifluoromethyl)-phenylboronic acid (CAS 1310403-90-7), molecular formula C7H4BBrClF3O2 and molecular weight 303.27 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Bromo-2-chloro-3-(trifluoromethyl)-phenylboronic acid (C7H4BBrClF3O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Bromo-2-chloro-3-(trifluoromethyl)-phenylboronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4BBrClF3O2 |
| Molecular Weight | 303.27 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl/Br-containing |
Related Bromo Standards
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