4-Chloro-3-(difluoromethoxy)phenylboronic acid CAS 1310949-72-4
| CAS No. | 1310949-72-4 |
| Molecular Formula | C7H6BClF2O3 |
| Molecular Weight | 222.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-Chloro-3-(difluoromethoxy)phenylboronic acid (C7H6BClF2O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
4-Chloro-3-(difluoromethoxy)phenylboronic acid (CAS 1310949-72-4) is a high-purity analytical reference standard with the molecular formula C7H6BClF2O3 and a molecular weight of 222.38 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Chloro-3-(difluoromethoxy)phenylboronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H6BClF2O3 |
| Molecular Weight | 222.38 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- (3-Chloro-2,6-difluoro-4-methoxyphenyl)boronic acid (CAS 1298047-44-5)
- (2-Chloro-4-(difluoromethoxy)phenyl)boronic acid (CAS 313545-33-4)
- [3-Chloro-5-(difluoromethoxy)phenyl]boronic acid (CAS 2377611-72-6)
- 4-Chloro-2,3-difluoro-5-methoxyphenylboronic acid (CAS 2121513-09-3)
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