4-Chloro-2,3-difluoro-5-methoxyphenylboronic acid CAS 2121513-09-3
| CAS No. | 2121513-09-3 |
| Molecular Formula | C7H6BClF2O3 |
| Molecular Weight | 222.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-Chloro-2,3-difluoro-5-methoxyphenylboronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 4-Chloro-2,3-difluoro-5-methoxyphenylboronic acid (CAS 2121513-09-3), a certified reference material (molecular formula C7H6BClF2O3, MW 222.38 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 4-Chloro-2,3-difluoro-5-methoxyphenylboronic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 222.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H6BClF2O3 |
| Molecular Weight | 222.38 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- (3-Chloro-2,6-difluoro-4-methoxyphenyl)boronic acid (CAS 1298047-44-5)
- 4-Chloro-3-(difluoromethoxy)phenylboronic acid (CAS 1310949-72-4)
- (2-Chloro-4-(difluoromethoxy)phenyl)boronic acid (CAS 313545-33-4)
- [3-Chloro-5-(difluoromethoxy)phenyl]boronic acid (CAS 2377611-72-6)
- 2-(((3-Chloro-4-methylphenyl)amino)methyl)isoindoline-1,3-dione (CAS 84501-73-5)
- (2-Chloro-4-(1H-imidazol-1-yl)phenyl)boronic acid (CAS 2225180-94-7)
- (2-Chloro-4-(1H-pyrazol-1-yl)phenyl)boronic acid (CAS 2225180-95-8)
- (3-Chloro-4-(1H-imidazol-1-yl)phenyl)boronic acid (CAS 2225177-00-2)
Recommended Standards
- 2,4-Di-tert-butylthiophenol (CAS 19728-43-9)
- 4-((Trimethylsilyl)ethynyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1015609-91-2)
- 6-(Trimethylsilyl)benzo[d]thiazol-2-amine (CAS 131395-09-0)
- tert-Butyldimethyl(p-tolyloxy)silane (CAS 62790-85-6)
- (R)-1-(4-Cyclohexylphenyl)ethan-1-ol (CAS 1134545-73-5)
- N-(tert-Butyl)-6-(4-methylpiperazin-1-yl)-4-(o-tolyl)nicotinamide (CAS 881743-64-2)
- 2,4,5,6,7,8-Hexahydrocyclohepta[c]pyrazole-3-carboxylic acid (CAS 842972-72-9)
- 3-Fluoro-2-(trifluoromethoxy)benzaldehyde (CAS 1806303-16-1)
- 4-Benzyl-1-(3-chloropropyl)piperidine (CAS 136718-81-5)
- 2-(8-Fluoronaphthalen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2621932-49-6)
- Methyl 3-hydroxytetrahydro-2H-pyran-4-carboxylate (CAS 1510045-74-5)
- N-(4-methoxyphenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxamide hydrochloride (CAS 1220020-57-4)
- 4,5-Dichloro-2-methylphenol (CAS 52780-67-3)
- Tirzepatide Impurity 52 (CAS CATO-C4X-324052)
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