2H-Indazole-6-sulfonyl chloride CAS 131290-01-2
| CAS No. | 131290-01-2 |
| Molecular Formula | C7H5ClN2O2S |
| Molecular Weight | 216.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2H-Indazole-6-sulfonyl chloride (C7H5ClN2O2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
2H-Indazole-6-sulfonyl chloride (CAS 131290-01-2), molecular formula C7H5ClN2O2S and molecular weight 216.64 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2H-Indazole-6-sulfonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5ClN2O2S |
| Molecular Weight | 216.64 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related H Standards
- 1H-Indazole-4-sulfonyl chloride (CAS 858227-51-7)
- 1H-Indazole-5-sulfonyl chloride (CAS 599183-35-4)
- 1H-indazole-6-carboxylic acid, 1-acetyl-, methyl ester (CAS 1027022-60-1)
- 1H-indazole-4-carboxylic acid, 1-acetyl-, methyl ester (CAS 1027991-36-1)
- (1h-Indazole-3-carbonyl)glycine (CAS 403483-02-3)
- Indazole Impurity 3 (CAS 1801267-04-8)
- 1H-indazole-5-carboxylic acid, 3-(Hydroxymethyl)-, methyl ester (CAS 1246250-09-8)
- 1H-Indazole-3,7-dicarboxylic acid (CAS 1427504-82-2)
Recommended Standards
- 1-(2-Chloro-5-fluoropyrimidin-4-yl)pyrrolidin-3-amine (CAS 1310558-47-4)
- BENZOFURAN-6-SULFONYL CHLORIDE (CAS 1314920-96-1)
- (R)-2-amino-N-(3-chloro-4-fluorophenyl)propanamide (CAS 1304836-00-7)
- 5-cyano-6-methylpyridine-3-sulfonyl chloride (CAS 1346534-17-5)
- 5-(Cyclohexylsulfonyl)-2-(methylthio)thiazol-4-amine (CAS 117420-90-3)
- (Z)-2-Phenyl-4-((propylthio)methylene)oxazol-5(4H)-one (CAS 61861-53-8)
- 2-Isobutyl-5-(methylamino)-1,2,4-thiadiazol-3(2H)-one (CAS 1365942-26-2)
- 5-Bromo-2-(4-ethylpiperazin-1-yl)aniline (CAS 1016794-10-7)
- Azasetron-13C,D3 Hydrochloride (CAS 1329611-23-5)
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- 3-(4-Ethoxyphenyl)-2-sulfanyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3h)-one (CAS 65234-03-9)
- 2-(2-Formyl-1h-pyrrol-1-yl)benzoic acid (CAS 55540-44-8)
- Dacomitinib Impurity 44 (CAS CATO-C4X-208644)
- Tau Peptide (401-411)-Lys-Lys trifluoroacetate salt (CAS 2022956-59-6)
Why CATO?
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