Betamethasone Impurity 122 CAS CATO-C4X-1437122
| CAS No. | CATO-C4X-1437122 |
| Molecular Formula | C24H30O5 |
| Molecular Weight | 398.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Betamethasone Impurity 122 is closely related to a flavonoid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Betamethasone Impurity 122 (CAS CATO-C4X-1437122, C24H30O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Betamethasone Impurity 122 (C24H30O5) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Betamethasone Impurity 122 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H30O5 |
| Molecular Weight | 398.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Betamethasone Standards
- Betamethasone Impurity N1 (CAS 910-99-6)
- Betamethasone Impurity 112 (CAS CATO-C4X-1437112)
- Betamethasone Impurity 121 (CAS CATO-C4X-1437121)
- Betamethasone Impurity 89 (CAS CATO-C4X-143789)
- Betamethasone-d5 (CAS CATO-CCAD301382)
- Betamethasone Impurity 86 (CAS 560-34-9)
- Betamethasone Impurity 136 (CAS CATO-C4X-1437136)
- Betamethasone Impurity 38 (CAS 25121-04-4)
Recommended Standards
- Eplerenone Impurity 11 (CAS 192704-70-4)
- Eplerenone EP Impurity C (CAS 95716-70-4)
- Budesonide Impurity 14 (CAS 5541-37-7)
- Norethindrone Impurity 11 (CAS CATO-C4X-171311)
- Goserelin Impurity 40 Trifluoroacetic Acid (CAS CATO-C4X-192040)
- Piribedil Impurity N4 (CAS 55436-41-4)
- Proguanil EP Impurity G (CAS 807308-41-4)
- methyl thieno[2,3-b]pyridine-5-carboxylate (CAS 21344-30-9)
- 2-Amino-1-(3-hydroxyphenyl)ethanone (CAS 90005-54-2)
- (3aS,6aS)-5-(3-methylbenzenesulfonyl)-octahydropyrrolo[3,4-b]pyrrole hydrochloride (CAS 1807933-98-7)
- 3,4-Bis[(9R)-cinchonan-9-ylamino]-3-cyclobutene-1,2-dione (CAS 1255087-70-7)
- Ethyl 2-bromo-4-phenylbutanoate (CAS 82586-61-6)
- methyl 1-butyl-1H-pyrazole-5-carboxylate (CAS 1171168-74-3)
- [Formaldehyde Schiff-base]-Semaglutide Impurity 136 X TFA Salt (CAS CATO-C4X-2226136)
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