4-(4-Chlorobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid CAS 1326809-93-1
| CAS No. | 1326809-93-1 |
| Molecular Formula | C18H23ClN2O4 |
| Molecular Weight | 366.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-(4-Chlorobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326809-93-1) is a high-purity analytical reference standard with the molecular formula C18H23ClN2O4 and a molecular weight of 366.84 g/mol.
The molecular framework of 4-(4-Chlorobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (C18H23ClN2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 4-(4-Chlorobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H23ClN2O4 |
| Molecular Weight | 366.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorobenzoyl Standards
- 4-(3-Chlorobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326809-11-3)
- 4-(2-Chlorobenzoyl)-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326809-25-9)
- Ethyl 2-{2-[(4-chlorobenzoyl)amino]-1,3-thiazol-4-yl}-2-(methoxyimino)acetate (CAS 1024870-00-5)
- Methyl 3-[(3-chlorobenzoyl)amino]-3-(1-naphthyl)propanoate (CAS 439108-87-9)
- 16-(4-Chlorobenzoyl)-11,15-dioxa-16-azatetracyclo[8.7.0.0^{2,7}.0^{13,17}]heptadeca-1(10),2(7),3,5,8-pentaene (CAS 477853-75-1)
- (E)-2-(2-Chlorobenzoyl)-3-[4-fluoro-3-(trifluoromethyl)anilino]-2-propenenitrile (CAS 1025596-46-6)
- N'-(3-chlorobenzoyl)naphtho[2,1-b]furan-2-carbohydrazide (CAS 478259-75-5)
- 5-(4-Chlorobenzoyl)-N2-(4-chlorophenyl)-1,3-thiazole-2,4-diamine (CAS 107401-72-9)
Recommended Standards
- 2-Chloro-4-[4-(1-naphthyl)phenyl]quinazoline (CAS 1373265-62-3)
- Atovaquone EP Impurity B (RC A) (CAS 137732-39-9)
- Dehydro Indapamide-d3 (CAS 1185057-48-0)
- 1-(2,4-Bis(benzyloxy)-5-chlorophenyl)ethanone (CAS 705963-54-8)
- (S)-2-(2-(3,5-Difluorophenyl)acetamido)-N-((S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)propanamide (CAS 209986-17-4)
- Mafosfamide (CAS 88859-04-5)
- 5-(Benzylsulfanyl)-4-(2,4-dichlorophenyl)-1,2,3-thiadiazole (CAS 338408-03-0)
- 3-(Dimethylamino)propanoic acid (CAS 6300-04-5)
- Ethyl 1-nicotinoylpiperidine-4-carboxylate (CAS 189300-75-2)
- Tert-butyl ((3S,5R)-1-(3-aminopyridin-4-yl)-5-(trifluoromethyl)piperidin-3-yl)carbamate (CAS 1620240-20-1)
- Methyl 4-(2-fluorophenyl)-4-oxobutanoate (CAS 1251115-66-8)
- (1R,2R)-1,2-Bis(perfluorophenyl)ethane-1,2-diamine dihydrochloride (CAS 1055301-07-9)
- 5-(Difluoromethyl)-3-methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (CAS 2923542-41-8)
- Insulin Degludec Impurity 12 (CAS CATO-C4X-215712)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com