Mesalazine Impurity 30 CAS 14474-22-7
| CAS No. | 14474-22-7 |
| Molecular Formula | C13H10N2O2 |
| Molecular Weight | 226.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Mesalazine Impurity 30 (C13H10N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Mesalazine Impurity 30 (CAS 14474-22-7), a pharmacopoeial impurity reference standard (molecular formula C13H10N2O2, MW 226.23 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H10N2O2 |
| Molecular Weight | 226.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 2 |
Related Mesalazine Standards
- Mesalazine Impurity 50 (CAS CATO-C4X-132450)
- Mesalazine Impurity 47 (CAS 13300-63-5)
- Mesalazine Impurity 54 (CAS CATO-C4X-132454)
- Mesalazine Impurity 28 (CAS 40038-46-8)
- Mesalazine EP Impurity I (CAS 3147-53-3)
- Mesalazine Impurity 53 (CAS CATO-C4X-132453)
- Mesalazine N-Propionyl Impurity (CAS 93968-80-0)
- Mesalazine Impurity 45 (CAS CATO-C4X-132445)
Recommended Standards
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