Prilocaine EP Impurity F HCl CAS 13327-14-5
| CAS No. | 13327-14-5 |
| Molecular Formula | C12H18N2O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Prilocaine EP Impurity F HCl (CAS 13327-14-5), a pharmacopoeial impurity reference standard (molecular formula C12H18N2OHCl, MW 242.75 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Prilocaine EP Impurity F HCl (C12H18N2OHCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 242.75 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H18N2O HCl |
| Molecular Weight | 242.75 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Prilocaine Standards
- Prilocaine Impurity 01 (CAS 103-89-9)
- Prilocaine EP Impurity G (CAS 1049712-77-7)
- Prilocaine Impurity 20 (CAS 1072844-57-5)
- Prilocaine Impurity C56 (CAS 111057-88-6)
- Prilocaine Impurity 25 (CAS 112843-97-7)
- Prilocaine Impurity 14 (CAS 120-66-1)
- Prilocaine Impurity 8 HCI (CAS 13438-26-1（free base）)
- Prilocaine (S)-Isomer (CAS 14289-31-7)
Recommended Standards
- Avanafil Impurity 16 (CAS CATO-C4X-111816)
- Vilazodone Impurity 02 (CAS 816438-46-7)
- Cefazolin EP Impurity J (CAS 1675245-00-7)
- 1-[4-(trifluoromethyl)benzoyl]piperidine (CAS 411209-38-6)
- 4,5,6,7-Tetrahydro-[1,2,3]triazolo[1,5-a]pyrazine dihydrochloride (CAS 165894-38-2)
- N-(2,3-dichlorophenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)acetamide (CAS 303091-19-2)
- 1-(2-Chloro-8-isopropylquinolin-3-yl)ethanol (CAS 1017463-49-8)
- 2,3,5-Trimethyl-4-phenylfuran (CAS 88928-40-9)
- Amyltriethylammonium Bis(trifluoromethanesulfonyl)imide (CAS 906478-91-9)
- Exenatide (CAS 141758-74-9（free base）)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com