3-chloro-1-(3,3-difluoroazetidin-1-yl)propan-1-one CAS 1334240-54-8
| CAS No. | 1334240-54-8 |
| Molecular Formula | C6H8ClF2NO |
| Molecular Weight | 183.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-chloro-1-(3,3-difluoroazetidin-1-yl)propan-1-one (CAS 1334240-54-8) is a high-purity analytical reference standard with the molecular formula C6H8ClF2NO and a molecular weight of 183.58 g/mol.
The molecular framework of 3-chloro-1-(3,3-difluoroazetidin-1-yl)propan-1-one (C6H8ClF2NO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-chloro-1-(3,3-difluoroazetidin-1-yl)propan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H8ClF2NO |
| Molecular Weight | 183.58 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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