Ethyl 5,7-difluoro-3-iodo-1H-indole-2-carboxylate CAS 1334499-90-9
| CAS No. | 1334499-90-9 |
| Molecular Formula | C11H8F2INO2 |
| Molecular Weight | 351.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Ethyl 5,7-difluoro-3-iodo-1H-indole-2-carboxylate (CAS 1334499-90-9) is a high-purity analytical reference standard with the molecular formula C11H8F2INO2 and a molecular weight of 351.09 g/mol.
Based on its molecular formula C11H8F2INO2, Ethyl 5,7-difluoro-3-iodo-1H-indole-2-carboxylate contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 351.09 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 5,7-difluoro-3-iodo-1H-indole-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8F2INO2 |
| Molecular Weight | 351.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 1 |
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- Almotriptan Impurity 12 (CAS CATO-C4X-153812)
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- 1-((5-(3-Chlorophenyl)-1,2,4-oxadiazol-3-yl)methyl)pyrrolidin-2-one (CAS 1357728-90-5)
- Semaglutide impurity 43 (CAS CATO-C4X-222643)
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