3,4-Difluoro-N-(tetrahydro-2H-pyran-4-yl)-N-(2-(thiophen-2-yl)ethyl)benzamide CAS 1797140-48-7
| CAS No. | 1797140-48-7 |
| Molecular Formula | C18H19F2NO2S |
| Molecular Weight | 351.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
3,4-Difluoro-N-(tetrahydro-2H-pyran-4-yl)-N-(2-(thiophen-2-yl)ethyl)benzamide (CAS 1797140-48-7), molecular formula C18H19F2NO2S and molecular weight 351.41 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 3,4-Difluoro-N-(tetrahydro-2H-pyran-4-yl)-N-(2-(thiophen-2-yl)ethyl)benzamide (C18H19F2NO2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 351.41 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H19F2NO2S |
| Molecular Weight | 351.41 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 1-(Tert-butyl) 4-ethyl 3-(4-fluorophenyl)piperidine-1,4-dicarboxylate (CAS 1432675-99-4)
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- 1-(tert-Butyl) 2-methyl 3-(4-fluorobenzyl)-1,2-piperidinedicarboxylate (CAS 1424941-19-4)
- 4-Cyano-3-fluorophenyl 4-(trans-4-ethylcyclohexyl)benzoate (CAS 92118-81-5)
- tert-Butyl (4-((2-hydroxyethyl)thio)cyclohexyl)carbamate (CAS 1353980-06-9)
- 3-(Chloromethyl)-5-(trifluoromethoxy)pyridine (CAS 1060815-05-5)
- 2-(4-bromophenyl)-1,3-thiazol-4-amine (CAS 1555162-42-9)
- 2,2',3,3',4,5,5',6'-Octachlorobiphenyl (CAS 52663-75-9)
- Methyl (S)-5-Oxo-1-[(S)-1-phenylethyl]pyrrolidine-3-carboxylate (CAS 146348-14-3)
- Ethyl 1-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)piperidine-4-carboxylate (CAS 135127-54-7)
- 4-(2-(Allyloxy)phenyl)-1H-pyrrole-3-carbonitrile (CAS 87388-23-6)
- 8-Ethoxyquinoline-5,7-diamine (CAS 99857-02-0)
- 2-Amino-6-methanesulfonylbenzonitrile (CAS 77326-37-5)
- Semaglutide impurity 202 (CAS CATO-C4X-2226202)
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