Ethyl (E)-2-cyano-3-(4-hydroxy-3-methoxyphenyl)acrylate CAS 13373-29-0
| CAS No. | 13373-29-0 |
| Molecular Formula | C13H13NO4 |
| Molecular Weight | 247.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl (E)-2-cyano-3-(4-hydroxy-3-methoxyphenyl)acrylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ethyl (E)-2-cyano-3-(4-hydroxy-3-methoxyphenyl)acrylate (CAS 13373-29-0) is a high-purity analytical reference standard with the molecular formula C13H13NO4 and a molecular weight of 247.25 g/mol.
The molecular framework of Ethyl (E)-2-cyano-3-(4-hydroxy-3-methoxyphenyl)acrylate (C13H13NO4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H13NO4 |
| Molecular Weight | 247.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
| Nitrogen Atoms | 1 |
Recommended Standards
- Ethyl 2-(3-methoxyphenyl)oxazole-4-carboxylate (CAS 132089-44-2)
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- 2-Nitrofluoranthene (CAS 13177-29-2)
- 2-(Amino(2-methoxyphenyl)methyl)-1H-imidazole-5-carboxylic acid (CAS 1344688-03-4)
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- 3,6-Dibromoimidazo[1,2-a]pyrazine (CAS 1245647-43-1)
- Exenatide (CAS 141758-74-9（free base）)
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