2-((3-(4-Bromophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide CAS 133764-46-2

Purity 97%+In StockPharmaceutical Standards
CAS No.133764-46-2
Molecular FormulaC16H13BrN4O2S
Molecular Weight405.27 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-((3-(4-Bromophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide CAS 133764-46-2 chemical structure

Description

The molecular framework of 2-((3-(4-Bromophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide (C16H13BrN4O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

CATO supplies 2-((3-(4-Bromophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide (CAS 133764-46-2), a certified reference material (molecular formula C16H13BrN4O2S, MW 405.27 g/mol) for analytical method development and quality control.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC16H13BrN4O2S
Molecular Weight405.27 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentBr-containing
Nitrogen Atoms4
Sulfur Atoms1

Related Bromophenyl Standards

Recommended Standards

Why CATO?