4-Chloro-3-(3-iodophenyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine CAS 1337880-80-4
| CAS No. | 1337880-80-4 |
| Molecular Formula | C11H7ClIN5 |
| Molecular Weight | 371.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-Chloro-3-(3-iodophenyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine (C11H7ClIN5) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 4-Chloro-3-(3-iodophenyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine (CAS 1337880-80-4), a certified reference material (molecular formula C11H7ClIN5, MW 371.56 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H7ClIN5 |
| Molecular Weight | 371.56 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 5 |
Related Chloro Standards
- 4-Chloro-3-(4-iodophenyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine (CAS 1337879-90-9)
- 4-Chloro-3-(2-iodophenyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine (CAS 1337882-24-2)
- 4-Chloro-3-iodo-2-methyl-6-(trifluoromethyl)quinoline (CAS 1431365-65-9)
- N-(2-Chloro-4-iodophenyl)-3-methylbenzamide (CAS 424816-35-3)
- N-(2-Chloro-4-iodophenyl)-4-methylbenzamide (CAS 424815-38-3)
- N-[4-Chloro-2-(Trifluoromethyl)Phenyl]-1-[2,3-Dichloroprop-2-Enyl]Pyrrolidin-2-Imine (CAS 32280-92-5)
- 2-(2-Chloro-4-fluoro-5-nitrophenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene (CAS 2244085-06-9)
- 5-chloro-3-iodo-1-(oxan-2-yl)-1H-pyrazolo[4,3-b]pyridine (CAS 1416713-15-9)
Recommended Standards
- Tetradecanoylcarnitine (CAS 25597-07-3)
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- 9-[3-(Triethoxysilyl)propyl]carbazole (CAS 221105-38-0)
- 2,6-Dichloro-4-(pentafluoro-lambda6-sulfanyl)benzenesulfonyl chloride (CAS 1706430-41-2)
- 6-Iodothieno[3,2-d]pyrimidin-4(3H)-one (CAS 1021346-04-2)
- Copper Oxychloride (CAS 1332-40-7)
- Ethyl 4-cyano-3-oxobutanoate (CAS 1715-68-0)
- 3-(4-Fluoro-2-methylbenzyl)pyrrolidine (CAS 1337189-37-3)
- 3-(2-Bromoethyl)pyridineDISCONTINUED, offer B801798 (CAS 120277-73-8)
- (5-(1H-Imidazol-5-yl)furan-2-yl)methanamine (CAS 252054-00-5)
- (S)-tert-butyl(phenyl)phosphinothioic s-acid (CAS 55705-77-6)
- n-[(3-methoxyphenyl)methylidene]hydroxylamine (CAS 52707-52-5)
- H-Val-Gln-OH (CAS 42854-54-6)
- Semaglutide impurity 88 (CAS CATO-C4X-222688)
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