4-Chloro-3-(2-iodophenyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine CAS 1337882-24-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1337882-24-2
Molecular FormulaC11H7ClIN5
Molecular Weight371.56 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Chloro-3-(2-iodophenyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine CAS 1337882-24-2 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO supplies 4-Chloro-3-(2-iodophenyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine (CAS 1337882-24-2), a certified reference material (molecular formula C11H7ClIN5, MW 371.56 g/mol) for analytical method development and quality control.

The molecular framework of 4-Chloro-3-(2-iodophenyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine (C11H7ClIN5) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

CATO manufactures 4-Chloro-3-(2-iodophenyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC11H7ClIN5
Molecular Weight371.56 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentCl/I-containing
Nitrogen Atoms5

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