Cetirizine Impurity C18 CAS 13391-39-4
| CAS No. | 13391-39-4 |
| Molecular Formula | C13H10Cl2 |
| Molecular Weight | 237.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Cetirizine Impurity C18 is closely related to chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Cetirizine Impurity C18 (CAS 13391-39-4), a pharmacopoeial impurity reference standard (molecular formula C13H10Cl2, MW 237.12 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Cetirizine Impurity C18 (C13H10Cl2) contains chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 237.12 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Cetirizine Impurity C18 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H10Cl2 |
| Molecular Weight | 237.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
| Halogen Content | Cl-containing |
Related Cetirizine Standards
- Cetirizine Impurity 28 (CAS CATO-C4X-158228)
- Cetirizine Impurity 10 (CAS 1016-78-0)
- Cetirizine Impurity 22 (CAS 13391-38-3)
- Cetirizine impurity N1 (CAS 58023-19-1)
- Cetirizine EP Impurity A (CAS 303-26-4)
- Cetirizine Impurity Y (CAS 34605-45-3)
- Cetirizine Impurity 35 (CAS CATO-C4X-158235)
- Cetirizine Impurity 36 (CAS CATO-C4X-158236)
Recommended Standards
- Tantalum silicide (99.5%-Ta) (CAS 12039-79-1)
- 4-Chlorobenzhydryl Chloride (CAS 134-83-8)
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- 5,6-Dichloropyrazine-2,3-diamine (CAS 13484-57-6)
- Crizotinib Impurity 48 (CAS CATO-C4X-102548)
- Ambroxol Impurity 38 hydrochloride (CAS 2356152-56-0)
- Sildenafil EP Impurity F (CAS 139755-82-1)
- 8-Methoxy-1,2,3,4-tetrahydro-quinoline (CAS 53899-17-5)
- (S)-1-(D-Phenylalanyl)-N-((S)-5-guanidino-1-((4-nitrophenyl)amino)-1-oxopentan-2-yl)piperidine-2-carboxamide (CAS 64815-81-2)
- 4-Fluoro-N-[6-(morpholin-4-yl)pyridin-3-yl]benzamide (CAS 383146-19-8)
- [S(R)]-N-[(S)-[4-(1,1-Dimethylethyl)phenyl][5-(diphenylphosphino)-9,9-dimethyl-9H-xanthen-4-yl]methyl]-2-methyl-2-propanesulfinamide (CAS 2160535-59-9)
- 3-{[(tert-butoxy)carbonyl](methyl)amino}benzoic acid (CAS 168162-30-9)
- N-(cyclohexylmethyl)-2,2-dimethylthietan-3-amine (CAS 1880362-21-9)
- D-Tyr10-Tirzepatide (CAS CATO-CPTD788922)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com