2-(5-Bromothiophen-2-yl)pyrimidine-4-carboxylic acid CAS 1340293-55-1
| CAS No. | 1340293-55-1 |
| Molecular Formula | C9H5BrN2O2S |
| Molecular Weight | 285.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(5-Bromothiophen-2-yl)pyrimidine-4-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-(5-Bromothiophen-2-yl)pyrimidine-4-carboxylic acid (CAS 1340293-55-1), a certified reference material (molecular formula C9H5BrN2O2S, MW 285.12 g/mol) for analytical method development and quality control.
The molecular framework of 2-(5-Bromothiophen-2-yl)pyrimidine-4-carboxylic acid (C9H5BrN2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(5-Bromothiophen-2-yl)pyrimidine-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H5BrN2O2S |
| Molecular Weight | 285.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Bromothiophen Standards
- 2-(5-bromothiophen-2-yl)pyrimidine-5-carboxylic acid (CAS 1343187-78-9)
- Ethyl 2-(5-bromothiophen-2-yl)-2,2-difluoroacetate (CAS 1286792-85-5)
- 2-(4-Bromothiophen-2-yl)-5,6-dimethylpyrimidin-4-amine (CAS 1251313-29-7)
- (2-(5-Bromothiophen-2-yl)-6-methylpyrimidin-4-yl)methanamine (CAS 1339218-94-8)
- 1-(4-Bromothiophen-2-yl)-N-(pyrimidin-5-ylmethyl)methanamine (CAS 1340322-00-0)
- n-((5-Bromothiophen-2-yl)methyl)furan-2-carboxamide (CAS 1090552-81-0)
- 1-((4-Bromothiophen-2-yl)methyl)-1H-pyrrole-3-carboxylic acid (CAS 1515396-01-6)
- n-((3-Bromothiophen-2-yl)methyl)-2-fluoroaniline (CAS 1248610-49-2)
Recommended Standards
- (5-((3,4-Dihydroquinolin-1(2H)-yl)methyl)-2-fluorophenyl)boronic acid (CAS 1332653-99-2)
- (4-(2-Bromoethyl)phenyl)(trifluoromethyl)sulfane (CAS 1343048-83-8)
- 3-Nitro-5-(perfluoroethyl)benzoic acid (CAS 1229625-32-4)
- (2-Methyl-4-(morpholinosulfonyl)phenyl)boronic acid (CAS 1217501-53-5)
- Dehydroandrosterone Acetate (CAS 5223-99-4)
- 2-(4-Chloro-1h-pyrazol-1-yl)-5-fluorobenzaldehyde (CAS 1183264-59-6)
- 4-Chloro-2-((4-fluorobenzyl)thio)pyridine (CAS 1346707-45-6)
- 3-(3-Bromo-5-fluorophenyl)propanoic acid (CAS 1261680-57-2)
- (R)-1-(2-(Hydroxymethyl)-4-nitrophenyl)pyrrolidin-3-ol (CAS 851690-85-2)
- (5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl phenylcarbamate (CAS 318248-39-4)
- Roxatidine Impurity 26 (CAS CATO-C4X-121326)
- 2-(methanesulfonylmethyl)-1,3-oxazole-4-carboxylic acid (CAS 1338976-77-4)
- BCAT (CAS 163853-10-9)
- Mast Cell Degranulating Peptide (CAS 83856-13-7)
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