Ethyl 2-(5-bromothiophen-2-yl)-2,2-difluoroacetate CAS 1286792-85-5
| CAS No. | 1286792-85-5 |
| Molecular Formula | C8H7BrF2O2S |
| Molecular Weight | 285.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies Ethyl 2-(5-bromothiophen-2-yl)-2,2-difluoroacetate (CAS 1286792-85-5), a certified reference material (molecular formula C8H7BrF2O2S, MW 285.11 g/mol) for analytical method development and quality control.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system, Ethyl 2-(5-bromothiophen-2-yl)-2,2-difluoroacetate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 285.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7BrF2O2S |
| Molecular Weight | 285.11 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Br-containing |
| Sulfur Atoms | 1 |
Related Ethyl Standards
- 2-(5-Bromothiophen-2-yl)pyrimidine-4-carboxylic acid (CAS 1340293-55-1)
- 2-(5-bromothiophen-2-yl)pyrimidine-5-carboxylic acid (CAS 1343187-78-9)
- 2-(4-Bromothiophen-2-yl)-5,6-dimethylpyrimidin-4-amine (CAS 1251313-29-7)
- (2-(5-Bromothiophen-2-yl)-6-methylpyrimidin-4-yl)methanamine (CAS 1339218-94-8)
- 1-(4-Bromothiophen-2-yl)-N-(pyrimidin-5-ylmethyl)methanamine (CAS 1340322-00-0)
- n-((5-Bromothiophen-2-yl)methyl)furan-2-carboxamide (CAS 1090552-81-0)
- 1-((4-Bromothiophen-2-yl)methyl)-1H-pyrrole-3-carboxylic acid (CAS 1515396-01-6)
- n-((3-Bromothiophen-2-yl)methyl)-2-fluoroaniline (CAS 1248610-49-2)
Recommended Standards
- Ibandronic Impurity 6 (CAS 63132-39-8)
- 3-Thiopheneacetic acid, 4-bromo-α,α-difluoro-, ethyl ester (CAS 1537724-16-5)
- Furosemide Impurity 44 (CAS CATO-C4X-140244)
- 2-(2-Bromo-5-fluorophenoxy)-3-(dimethylamino)acrylonitrile (CAS 1620478-72-9)
- 3'-(Trifluoromethyl)-3,6-dihydro-2H-[1,2'-bipyridine]-4-carbonitrile (CAS 801306-56-9)
- 2,3-Dimethylimidazo[1,2-a]pyridin-6-amine (CAS 1082303-17-0)
- 4-Bromo-3-(difluoromethyl)-6-methoxypyridine-2-carbonyl chloride (CAS 1805426-58-7)
- (R)-5,7-dichloro-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 1241684-14-9)
- 3-Bromopyrazolo[1,5-a]pyridine-6-carboxylic acid (CAS 1784165-05-4)
- Benzbromarone Impurity 9 (CAS 3131-63-3)
- Methyl 4-iodo-1H-imidazole-5-carboxylate (CAS 1379328-34-3)
- 2-Hydroxy-N-[5-(methoxymethyl)-1,3,4-thiadiazol-2-yl]benzamide (CAS 893778-57-9)
- 3-[(4-Isopropylphenyl)methyl]azetidine 3-[[(4-(1-methylethyl)phenyl]methyl]azetidine 937622-20-3 (CAS 937622-20-3)
- 1-His-N-a-ethylidene Semaglutide (CAS CATO-C4X-2226252)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com