2-(5-bromothiophen-2-yl)pyrimidine-5-carboxylic acid CAS 1343187-78-9
| CAS No. | 1343187-78-9 |
| Molecular Formula | C9H5BrN2O2S |
| Molecular Weight | 285.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 285.12 g/mol gives 2-(5-bromothiophen-2-yl)pyrimidine-5-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-(5-bromothiophen-2-yl)pyrimidine-5-carboxylic acid (CAS 1343187-78-9), a certified reference material (molecular formula C9H5BrN2O2S, MW 285.12 g/mol) for analytical method development and quality control.
2-(5-bromothiophen-2-yl)pyrimidine-5-carboxylic acid (C9H5BrN2O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H5BrN2O2S |
| Molecular Weight | 285.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related bromothiophen Standards
- 2-(5-Bromothiophen-2-yl)pyrimidine-4-carboxylic acid (CAS 1340293-55-1)
- Ethyl 2-(5-bromothiophen-2-yl)-2,2-difluoroacetate (CAS 1286792-85-5)
- 2-(4-Bromothiophen-2-yl)-5,6-dimethylpyrimidin-4-amine (CAS 1251313-29-7)
- (2-(5-Bromothiophen-2-yl)-6-methylpyrimidin-4-yl)methanamine (CAS 1339218-94-8)
- 1-(4-Bromothiophen-2-yl)-N-(pyrimidin-5-ylmethyl)methanamine (CAS 1340322-00-0)
- n-((5-Bromothiophen-2-yl)methyl)furan-2-carboxamide (CAS 1090552-81-0)
- 1-((4-Bromothiophen-2-yl)methyl)-1H-pyrrole-3-carboxylic acid (CAS 1515396-01-6)
- n-((3-Bromothiophen-2-yl)methyl)-2-fluoroaniline (CAS 1248610-49-2)
Recommended Standards
- (4-(2-Bromoethyl)phenyl)(trifluoromethyl)sulfane (CAS 1343048-83-8)
- 2-(Tert-butyl)-4-iodobenzonitrile (CAS 1369903-89-8)
- 4-(3-Bromophenyl)-1,2,3-thiadiazole-5-carboxylic acid (CAS 1482594-20-6)
- (5-((3,4-Dihydroquinolin-1(2H)-yl)methyl)-2-fluorophenyl)boronic acid (CAS 1332653-99-2)
- 6-Methyl-2-pyrazinyl-boronic Acid (CAS 1309981-13-2)
- 1-(4-Methoxy-phenyl)-1H-benzoimidazole-2-thiol (CAS 26495-07-8)
- (3-(5-Bromofuran-2-yl)phenyl)methanol (CAS 89929-92-0)
- 4-(4-Chlorophenyl)pyridin-3-amine (CAS 349483-97-2)
- Saikosaponin I (CAS 103629-71-6)
- 1-Chloroisoquinoline-7-carbonitrile (CAS 223671-30-5)
- Broussonin C (CAS 76045-49-3)
- 4-amino-2,4-dimethylpentanoic acid hydrochloride (CAS 1796942-55-6)
- (5-(Methoxymethyl)thiophen-2-yl)methanol (CAS 1211509-18-0)
- Calcineurin Autoinhibitory Peptide (CAS 148067-21-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com