Pentoxifylline EP Impurity E CAS 77196-87-3
| CAS No. | 77196-87-3 |
| Molecular Formula | C15H16N8O4 |
| Molecular Weight | 372.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Pentoxifylline EP Impurity E (C15H16N8O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 372.34 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Pentoxifylline EP Impurity E (CAS 77196-87-3), a pharmacopoeial impurity reference standard (molecular formula C15H16N8O4, MW 372.34 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H16N8O4 |
| Molecular Weight | 372.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Nitrogen Atoms | 8 |
Related Pentoxifylline Standards
- Pentoxifylline EP Impurity H (CAS 200556-62-3)
- Pentoxifylline EP Impurity K (CAS 74857-22-0)
- Pentoxifylline Impurity N2 (CAS 1243654-85-4)
- Pentoxifylline Impurity 26 (CAS CATO-C4X-172826)
- Pentoxifylline Impurity N4 (CAS 84321-40-4)
- Pentoxifylline impurity 37 (CAS CATO-C4X-172837)
- Pentoxifylline Impurity 17 (CAS 1185995-26-9)
- Pentoxifylline Impurity 18 (CAS 1185878-98-1)
Recommended Standards
- Doxofylline Impurity 15 (CAS CATO-C4X-151315)
- Travoprost Impurity 18 (CAS 53872-60-9)
- Sofosbuvir Impurity 46 (CAS 874638-80-9)
- Travoprost Related Compound 25 (CAS CATO-C4X-192525)
- Vildagliptin Impurity 20 (CAS 1983839-19-1)
- Doxorubicin Impurity 34 (CAS CATO-C4X-203334)
- Sitagliptin Impurity 63 (CAS 1864680-46-5)
- 2-(propan-2-yl)piperidine hydrochloride (CAS 1177339-95-5)
- Methyl 3-(isopropylamino)benzoate (CAS 1152539-33-7)
- N1-ethyl-N1-[(4,5,6,7-tetrafluorobenzo[b]furan-2-yl)methyl]ethan-1-amine (CAS 256525-90-3)
- methyl 4-(3-aminopropyl)benzoate hydrochloride (CAS 74733-37-2)
- N-Isopropyl-2-oxooxazolidine-3-sulfonamide (CAS 340185-09-3)
- 207802-43-5 Ethane-1,2-diamine--trichlorocobalt--water (3/1/2) DTXSID10746548 (CAS 207802-43-5)
- Semaglutide impurity 267 (CAS CATO-C4X-2226267)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com