Sulindac EP Impurity D CAS 134439-52-4

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.134439-52-4
Molecular FormulaC21H19FO3S
Molecular Weight370.44 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Sulindac EP Impurity D CAS 134439-52-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 370.44 g/mol gives Sulindac EP Impurity D distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Sulindac EP Impurity D (CAS 134439-52-4) is a certified pharmaceutical impurity reference standard with the molecular formula C21H19FO3S and a molecular weight of 370.44 g/mol.

Based on its molecular formula C21H19FO3S, Sulindac EP Impurity D contains a steroid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 370.44 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC21H19FO3S
Molecular Weight370.44 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF-containing
Sulfur Atoms1

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